704 
PSYCHOLOGY: W. R. MILES 
This subject had served during parts of twenty days, in all approximately 
seventy hours well distributed over a period of six months. The fact 
that he had showed the smallest positive effect of the alcohol was an 
especial reason for selecting him for the later tests. 
During this second series of six consecutive days (June 29 to July 4, 
1914, inclusive) the subject, who was a medical student, ^ was free from 
the usual duties of the school year. Although serving part of the time 
as an intern in a nearby hospital, he regarded the period as a vacation 
and could thus carefully regulate his daily habits. The last food before 
each experimental session was a hearty meal taken seven hours pre- 
viously from which coffee and tobacco were excluded. No alcohol 
was taken during the week other than that given in the laboratory. 
The experiments began at 8 a.m. and continued until 1 p.m., thus provid- 
ing a total session of five hours as contrasted with the three hour periods 
employed by Dodge and Benedict. In the former series the subject 
was working intensely and an effort was made to guard against any 
weekly rhythm that might exist on this account by having all the ex- 
periments come on the same day of the week. In our experiments there 
seemed no such logical reason for extending the sessons over a period 
of weeks; consequently the measurements were made on consecutive 
days, the alcohol being given on the second, fourth and sixth days. The 
giving of alcohol doses in this frequency may present the possibility of 
an additive effect. However, such an effect would apply even more to 
the normal days and thus theoretically a smaller resulting difference 
would be shown. 
The alcohol for each day was given in a single portion. The dose used 
was that designated by Dodge and Benedict as 'Dose A,' which con- 
tained 30 cc. of absolute alcohol, 7 cc. of orange infusion,^ 1 cc. of a strong 
infusion of quassia, a slight amount of saccharine for sweetening, and 
water to bring the volume to 150 cc. A mixture of the same volume 
and composition, but without the alcohol, served as the control dose for 
each of the three normal days. In giving the two mixtures, every effort 
was made to prevent the subject from distinguishing between the 
alcohol and control days and he had no way of knowing before the session 
what the dose for that particular day was to be. As the alcohol fre- 
quently produced sensations of warmth in the stomach and flatulency, 
the subject never failed to identify the mixture before the experiment 
was over, although he received no confirmatory information regarding 
his impression. Unfortunately only the 30 cc. dose could be used in 
the second series. This was in accordance with the expressed desire 
of the subject who insisted that the 45 cc. dose, which he had taken three 
