— 127 — 
filmarone as the only active butanone, which Boehm had over- 
looked. Without at all having read my work, he characterises my 
view that the specific substance of the fern, which is insoluble in water, 
must be diluted in a small quantity of fatty oil, and mixed with essential 
oil, as a "long since abandoned hypothesis". Only during the last few 
months I have treated two children for tapeworm with the adult dose 
of filmarone (without oils), with all possible precautions, and have 
been unsuccessful in both cases. With this unfavourable experience 
the reports agree, which are made from all sides, that in ankylostoma 
also the butanones alone do not act sufficiently. On the other hand, 
I have before me reports from totally different quarters, mentioning 
that the combination of butanones (dissolved in a small quantity of 
fat) with essential oils^), leaves nothing to be desired in certainty of 
action. 
As extract of fern contains only a very small quantity of essential 
oil, it is replaced by other vermifuge essential oils, — with which I 
entirely agree. Those hitherto mostly used are oil of turpentine and 
thymol, — which does not say that the others mentioned above may 
not perhaps act better than oil of turpentine. Thymol by itself also 
has an expelling action in ankylostoma^ but it does not act with sufficient 
certainty in all cases. — In how far the small quantity of essential 
kousso oil contained in fresh kousso has a share in the vermifuge action, 
has not yet been investigated; but this much is certain, that the sub- 
stance, when old and stale, does not expel the worm. Possibly the 
treatment may here also be greatly improved by the admixture of a 
vermifuge oil. The treatment with kamala, by itself uncertain, might, 
in combination for example with cineol, give better results than wit- 
hout this addition. 
12. Group of Antidotes. 
With narcotic poisons, such as chloral hydrates, trional, and morphia, 
injections or solutions of camphor are suitable in case the patient is 
found completely insensible and without reaction. The camphor- 
injections may also be found useful in the collapse-stage during the 
deprivation - treatment for morphinism. J. Hoffmann 2) has, as a 
matter of fact, only seen favourable results from the internal adminis- 
tration of camphor during such treatment. In acute phosphorus - 
poisoning, if the phosphorus has already been resorbed from the 
gastro-intestinal canal, we can no longer do any good with the usual 
^) Compare E.Schmidt, Chem. Centralbl. 1903, II. 390; H. Goldmann, 
Deutsche Arzte-Ztg. 1903, No. 5; Baker, Brit. med. Journ., 28. March 1903; 
Nagel, Deutsche med. Wochenschr. 1903, p. 545; Pharm. Ztg. 48 (1903), 436. 
2) Therap. Monatshefte 1902, No. 7. 
