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THE VETERINARY SCIENCE 
the normal. The maximum temperature is reached in from 
fifteen to eighteen hours. It does not become normal until 
after twenty-four to forty-eight hours. During this time the 
animal is very decidedly ill. The tumor at the point of 
injection increases in size for two or three days, and only 
disappears after several days. In a healthy horse, on the 
contrary, mallein in even much larger doses has no apprecia- 
ble constitutional effects. A small edematous swelling is 
formed at the site of injection, which is hot and slightly 
sensitive early, but soon diminishes in size and in about 
twenty-four hours entirely disappears. 
It is essential that the mallein be used as soon as the 
package is opened. 
The site of the injection (preferably the side of the neck) 
should be carefully shaved and disinfected, a 5-per-cent solu- 
tion of carbolic acid, or a 1 to 1000 solution of bichloride of 
mercury being used for this purpose. Careful sterilization of 
the syringe should be made before and after the injection, as 
directed. Mallein, as well as the syrifige, can be secured 
from the Detroit Instrument Co., Detroit, Mich. 
11. — Fevers. 
These are four in number, as follows: Influenza, Pur- 
pura Hemorrhagica (commonly known as Button Farcy), 
Strangles or Distemper, Epizootic Cellulitis (Pink Eye). 
1. Influenza. 
This disease received its name when, at one time, it was 
thought to be influenced by the stars. It is very common 
among horses of America, and is a disease that is liable to 
affect any organ of the body. 
Causes. — The germs of influenza float about in the air 
and in this manner is quickly communicated from one horse 
to another. It is more common in the spring and fall, when 
the horses are shedding their coats, than at any other time of 
the year. In 1874 and 1878 it broke out in the form of a 
regular epizootic, and spread all over the country, causing a 
great deal of trouble. Horses that are kept in badly-ven- 
tilated stables, especially those that are underground, are 
more subject to it. 
Symptoms. — Among the first symptoms are a dull, lan- 
guid appearance, a tendency to sweat upon the slightest 
