THOMPSON YATES AND JOHNSTON LABORATORIES REPORT 
Case VI 
Sleeping Sickness (September 30, 1903). — N'Bela, male, aged 24, agricultural 
labourer. A Mongo man. Patient never saw sleeping sickness before coming to 
Boma. Had lived in Boma tor nearly three years. Illness commenced in July of 
this year. Admitted to hospital, August 1, 1903. 
When the patient was seen (September 30) somnolence was already a marked 
feature of his condition. This symptom steadily became more marked as emaciation 
increased. When we left Boma (October 27) the patient was comatose, and death 
had been expected at any time during the preceding week. 
Genera/ Condition. — Patient is thin and very weak. Questions are answered 
rationally, but only after a long interval. He displays a somnolent indifference to 
everything about him, and only by constant shaking can drowsiness be dispelled for 
a period long enough to permit him to speak. 
Physical Examination. — Nervous system ; co-ordination imperfect. Sense of 
weight good. Knee-jerks and superficial reflexes were obtainable, and showed no 
abnormality. Eyes reacted to light and to accommodation. Thoracic and abdominal 
examination showed nothing worthy of note. Lymphatic glands were all enlarged, 
hard, and freely movable. There was no haemorrhage into mucous membranes. 
Slight icterus of the conjunctiva was seen. 
The accompanying chart indicates the course of the temperature in this case, and 
shows the results of the examinations for parasites. Trypanosomes were seen in both 
cerebro-spinal fluid and peripheral blood. 
On October 9, 35 c.cm. of slightly clouded, colourless cerebro-spinal fluid were 
taken by lumbar puncture. No red cells were seen in the fairly profuse deposit 
formed by centnfuging. This precipitate contained a fair number of trypanosomes, 
many monuclear cells of large size, and numerous polymorphonuclear leucocytes. 
Fx PERI MENTAL INOCULATION 
The following animals have been inoculated from this case. The material 
inoculated was in each case demonstrated to contain living trypanosomes. 
Animals Inoculated from Case 6 
October 7. White mouse (Experiment 16) inoculated subcutaneously with 
1 c.cm. cerebro-spinal fluid ; infected October 25. 
October 7. White mouse (Experiment 17) inoculated subcutaneously with 
1 c.cm. cerebro-spinal fluid ; never infected. 
September 30. White rat (Experiment 5) inoculated subcutaneously with 
5 c.cm. blood ; never infected. 
September 30. White rat (Experiment 6) inoculated intraperitoneally with 
1 c.cm. blood ; never infected. 
