8o THOMPSON YATES AND JOHNSTON LABORATORIES REPORT 
Goat. — One experiment, a female. Incubation period, nine days. Parasites were 
fairly constant in the blood during the first week of infection, but afterwards were 
found only rarely. There was no rise of temperature with the appearance of parasites 
in the blood, but five days later, when eight trypanosomes were seen to the cover, the 
temperature rose to 104' F. No other symptoms have as yet been observed. 
Donkey. — Inoculated on March 28 subcutaneously from a rat. On April 7 the 
temperature rose to 102-7° F., an d on the 9th to 103-2°. A rat inoculated from the 
donkey on April 8 showed parasites on the 26th. The incubation period in the 
donkey was therefore ten days. Parasites were seen for the first time in its blood 
on April 18, and again on the 22nd. 
Monkeys. — 1. Cercopitbecus callitrichus. Inoculated intraperitoneally on April 2 
from a rat. Trypanosomes appeared in the blood on the 6th, and were constantly 
present for a week, when they became rare, occasionally being absent altogether. On 
the 7th the temperature rose to 105-5° F., anc ^ nas smce been irregular (with 
occasional rises to 104° to 105°, and over). No other symptoms have so far been 
observed, the appetite is preserved, and the animal is in good condition. 2. Cercopi- 
tbecus callitrichus. Inoculated intraperitoneally on March 6 from a rat showing very 
few parasites. Trypanosomes did not appear in the blood before death, which took 
place from dysentery on the 10th. A monkey {Macacus rhesus), a rabbit, and one 
out of four rats inoculated with large doses of its heart blood became infected. Two 
guinea-pigs inoculated at the same time are still negative. Two mice inoculated with 
its blood died without becoming infected. 3. Macacus rhesus. Inoculated on 
March 10 intraperitoneally and subcutaneously with the heart blood of preceding 
monkey. Parasites were found in the blood on March 18, and were constantly 
oresent, although never very numerous, until April 6, when the animal died. On 
March 18 the temperature rose to 104-6°, with the appearance of parasites in the 
blood. During the last two days of life the temperature was subnormal (from 
95° to 96 J ). Diminution of red cells and haemoglobin was observed. Post-mortem, 
purulent peritonitis was found due to a parasite found in the intestinal walls, and not 
yet identified. 4. Macacus rhesus. Inoculated on March 14 intraperitoneally with 
the heart blood of a rat. Trypanosomes appeared in the blood on the 1 8th, and 
were fairly numerous for four days ; on the 31st there were from thirteen to eighteen 
to a field. They became rarer again before death, which occurred on April 1. The 
temperature rose on the 1 8th, and on the 19th reached 105-8°, there being six 
parasites to a field at the time. The red cells decreased from 4,000,000 to 2,500,000 
per cubic millimetre, and haemoglobin from fifty to twenty-seven per cent. 5. Macacus 
rhesus. Inoculated subcutaneously on April 22 with blood from a rabbit showing 
many trypanosomes. This monkey is not yet infected (April 27). 
