TWO CASES OF TRYPANOSOMIASIS IN EUROPEANS 
{Third Interim Report of the Expedition of the Liverpool School of Tropical Medicine 
to the Congo, 1903)* 
BY 
J. EVERETT DUTTON, M.B., Vict. 
WALTER MYERS FELLOW, UNIVERSITY OF LIVERPOOL 
JOHN L. TODD, B.A., M.D., CM., McGill 
AND 
CUTHBERT CHRISTY, M.B., Edin. 
THE following cases seem well worthy of record since they tend to indicate with 
what uniformity the accepted signs of the disease may be expected to occur 
in Europeans infected with Trypanosoma gamhiense. 
The completeness ot the history or the onset of the disease in Cases I and II 
makes them particularly interesting. The history of Case 1 is compiled from notes 
and temperature charts taken by the patient's husband during her illness. Case II was 
seen very soon after the probable date of his infection. 
Case I 
Mrs. G., aet. 35, a missionary. The patient's first stay in Congo was 
during the years 1895-99. During this period she had four small fevers, yielding to 
quinine — maximum temperature I03°F. ; and a supposed attack of haemoglobinuric 
fever. One year without fever was then spent in England, and in June, 1900, patient, 
weighing then 147 lbs., again went to the Congo. Soon after her return she had 
three attacks of fever — maximum temperature, 1 04 0 F. — which were successfully treated 
by quinine ; and from November, 1900, to July, 1901, she was in good health. 
During the first days of August, 1901, the patient took a long canoe journey 
from Bolobo to her station at Bongandanga on the Lopori, and was severely bitten by 
' river flies.' At the end of August, six days after the completion of the canoe trip, a 
severe fever commenced and lasted, without interruption, for twenty-five days. 'The 
highest temperature was 104° F., but the fever was very persistent and remained 
constant for two or three days at I03°F., then at I02°F., and so on. Quinine and 
phenacetin had no effect and the temperature was relieved only temporarily, but 
* Received for publication July. 
