8 THOMPSON YATES AND JOHNSTON LABORATORIES REPORT 
The following analyses were made by Mr. Edie, Laboratory for Bio-Chemistry : — 
Date 
Amount 
of Urine 
Sp. Gr. 
Reaction 
to 
Litmus 
Grams 
Total 
Nitrogen 
Grams 
Urea 
Grams 
Uric 
Acid 
Grams 
N H ., 
Grams 
NaCl 
Grams 
p 2 o. 
Albumen 
Sugar 
June 27 
860 
1014 

Acid 
10- 5 
21-3 
•43 
■26 
3-62 
„ 3° 
H+° 
IO I 9 
Alkaline 
17*9 
34" 1 
I-2 9 
•6 
I 2 '2 
2 '5 
July 13 
1 500 
IO17 
Acid 
I + -2 
28-2 
■52 
•76 
1 9"6 
1 "5 
„ 16 
1380 
I O I I 
Acid 
19-0 
'5 I 
•4 
"■3 
' 4 
s 
C 
I? 
1480 
IO.3 
Neutral 
12-6 
2 5"3 
•65 
•34 
io-8 
1 "35 
< 
< 
„ 22 
1 060 
1020 
Acid 
IO-5 
21-4 
•58 
"34 
111 
I - 2 
Aug. 1 
24.50 
IOI4 
Acid 
ZO'J 
4T9 
12 
■82 
24-8 
3 -0 
7 
2800 
IOl8 
Acid 
247 
49-2 
i*5 
'97 
23-1 
3 '4 
Nervous system : Knee jerks, cremasteric, epigastric, and anal reflexes normal. Electrical reactions 
normal, no tremors. Sensations, temperature, taste, and smell normal. No symptoms of drowsiness. 
No oedema, no skin eruption. The temperature ranged between 98 0 F. and I02'2° F., somewhat 
irregular ; sudden rises occurred which did not correspond with days on which an increased number 
of parasites was observed. 
The pulse was as usual rapid, 94-108, once or twice rising without apparent cause to 128, usually 
regular and of good volume ; after climbing or work, irregular and dicrotic. 
The man worked in the laboratory and animal houses. During the period of observation, from 
May 22 to August 15, no symptom other than the presence of parasites in the blood was noted. His 
appetite was inordinate and he grew extremely fat. No mental symptoms shewed themselves other than 
masturbation, which he had practised before arrival, and which he continued, despite all efforts to prevent it. 
Lumbar puncture performed once by Dr Christy, and twice while under observation, never shewed 
any parasites in the cerebro-spinal fluid, nor were animals infected by injections of the fluid. 
Lumbar puncture was performed three times in the Congo. Once trypanosomes were found but the 
notes record blood being mixed with the fluid at a period when eighty parasites to a cover were present 
in the peripheral blood. 
Gland examination : One cervical gland was removed and examined on a day when there were only a 
few parasites in the blood. The juice did not contain so many trypanosomes as did the blood. Glands 
were punctured on two occasions. On a day when the blood was negative no trypanosomes could be 
found in the fluid withdrawn from the gland. On the other time both gland and blood preparations 
contained the same number of trypanosomes. 
Blister fluid : "I he fluid contained no parasites, but successful infection of two mice out of four 
inoculated is recorded after a somewhat lengthened incubation period. This case was tried with injection 
of sodium arseniate, but as so much pain was complained of liquor arsenicalis was given by the mouth 
only to be discontinued and trypanroth gis. V in tabloid form substituted. To commence with one 
tabloid, later two tabloids a day were employed. No inconvenience appeared to be caused. The urine 
became pinkish twelve days after commencing treatment. A slight reddening of the conjunctivae appeared 
on the eighteenth day. The saliva appeared to have a faintly pinkish hue. The trypanosomes had 
