TRYPANOSOMES, TRYPANOSOMIASIS, AND SLEEPING SICKNESS 65 
SUPPLEMENTARY NOTES 
On some Animals still under Treatment on Drs. Thomas's and Breinl's 
Departure 
Nagana cow (page 55), died eleven days later. The haemoglobin was eighty 
per cent., and the agglutination of the red blood corpuscles remained absent. Death 
due to extensive hydatids and pulmonary tuberculosis. 
Surra horse (page 56), died over three weeks later. The haemoglobin which 
had at first risen under the atoxyl to eighty per cent, had fallen to sixty per cent, 
just before death. The agglutination of the red blood cells remained constantly 
present. In the intervals between the administration of the atoxyl, the parasites 
would return, and were twenty-five per field on the fourth day after the dose in the 
last week but one. Two doses per week were therefore commenced. This kept the 
number of parasites down, so that one per five fields was the highest reached. The 
animal, however, had become too reduced, and died three days after receiving the 
third dose at the smaller intervals. 
dutopsy. — There was anaemia of all the organs, otherwise (spleen not excepted) 
there were no striking naked eye changes. Patechial haemorrhages were found in the 
muscles of the chine. There was a retropharyngeal abscess the size of a child's head 
communicating with the nasal sinuses, but it appeared to have been of some standing 
and not to have caused death. The animal was able to swallow readily up to its 
death. 
Rabbit 839 (page 53), kept in perfect health for another month, and as the animal 
went off its food for a day or two the last dose given was only half the usual one. Two 
days later, however, the animal died, parasites having been found in the blood the 
day preceding, twenty per cover, degenerated and almost motionless from the effect 
of the atoxyl. 
Caderas rabbit (page 56), still alive, September 28, 1905. In perfect health. 
No discharges of any kind ; all hair regrown. No treatment since June 3. Blood 
negative since May 30 to microscopical examination. Its weight on April 25 was 
1,770 grammes, and continued to fall till the end of May, when it was 1,190 
grammes. Since then it has gradually increased to 1,795 grammes. It has now 
lived eight months. The head is usually kept over extended, which may be due to 
canker of the ears which was always present. 
P. A. H. RADCLIFFE, M.B. 
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