68 
THOMPSON YATES AND JOHNSTON LABORATORIES REPORT 
e llarged, being six cm. long and four cm. broad. On cross section they appeared 
uniformly yellowish in colour. 
Pieces were taken from all the organs and fixed in the usual fixing fluids : — 
Zenker's, Flemming's, hydrarg. perchlor., and alcohol. The brain and spinal cord 
were fixed in four per cent, formalin. 
Microscopical Examination 
The heart showed a fairly extensive small-celled infiltration in the endo-, epi-, and 
myocardium. The epicardial fat was well defined from the muscle, and in it was an 
accumulation of lymphocytes, large mononuclear and polymorphonuclear leucocytes. 
The infiltration extended along the connective tissue between the muscle fibres, and 
areas of infiltration were seen around some of the larger vessels in this situation, with 
a few mast cells and giant cells (these latter containing five to eight centrally-placed 
nuclei, or sometimes only fragments of nuclei). Here and there were large 
haemorrhages which extended from the perivascular connective tissue into the 
adjacent muscle, often destroying it. Frequently one could see, lying near a vessel 
wall, wedge-shaped patches of red blood corpuscles which were certainly the product 
of diapedesis, although no corpuscles were found in the wall itself. Many of the 
muscle fibres were smaller than normal, the striation was faint and around the nuclei 
were collections of reddish-brown pigment. These changes were for the most part 
equally distributed throughout the whole thickness of the myocardium, but in places 
were more marked in the left ventricle than in the right. 
For the detection of bacteria, sections were stained by Loffler's methylene 
blue, carbol fuchsin (Pfeiffer), carbol thionin and by Gram's method. Only a very 
few bacilli (decolourized by Gram's fluid) were found. These were considered to 
represent post-mortem contamination. 
Such parts of the lungs as appeared normal to the naked eye were found on 
microscopic examination to be hyperaemic. The congested vessels often contained 
a good number of white blood cells. The bronchi contained desquamated epithelium 
and exudation. The lymph tissue around the bronchi showed hyperplasia. The 
pleura showed various-sized extravasations of blood in its connective tissues, the blood 
vessels being very large. The pneumonic-looking parts showed typical catarrhal 
pneumonia, the alveoli were filled with red blood and exudation cells. The process 
had gone on further in some parts ; there the whole tissue formed a homogenous 
mass interspersed with red blood corpuscles and exudation cells. In the consolidated 
parts were a good number of cocci staining by Gram, and numerous GRAM-negative 
bacilli and cocci. 
The sections of the liver showed a thickening of the capsule. Between the chains 
of liver cells were many partly degenerated blood cells, decreasing in number as the 
centre of the liver was approached. The connective tissue was increased in amount 
