TRYP A.NOSOMES, TRYPANOSOMIASIS, AND SLEEPING SICKNESS 75 
With the above-mentioned bacteria-staining methods, microbes were only found 
in a few sections of the central nervous system, although very many sections were 
examined. They consisted of a few long bacilli in short chains and groups, and a few 
large cocci. The specimen stained by Gram's method showed no micro-organisms. 
B. — The Second Case, Tomi ; Died June 17, 1 904 
Post-mortem three hours after death. 
Length one hundred and fifty cm. ; very emaciated ; slightly built ; skin dry ; 
desquamating ; no particular pathological changes ; Rigor mortis commencing in 
upper extremities. Skull dolicho-cephalic. Pupils unequal, the right one smaller. 
Left eye showed a corneal opacity one mm. in diameter. Right eye, corneo-scleral 
junction at its right lower quadrant, ill defined, with peri-corneal injection 
corresponding. Conjuctivae and sclera pale ; slightly jaundiced. Mucous membrane 
of lips and mouth very pale. Neck short, thin, its hollows well marked. Glands on 
both sides of the sterno-mastoid muscle visible as slight elevations. Thorax barrel- 
shaped ; deeply indrawn intercostal spaces. Inguinal glands much enlarged ; skin 
over them elevated. External genitals normal. 
The under surface of scalp pale, here and there dark-blue, dilated veins visible. 
The circumference of skull fifty cm. ; skull cap thin with very numerous pacchionian 
depressions, especially along the coronal suture. Dura not tense, adherent to the 
bone ; inner surface smooth and glossy, no thickening nor haemorrhages ; all its 
sinuses filled with dark fluid blood. The amount of cerebro-spinal fluid was increased. 
The capillaries were injected ; the pia mater, especially along the edges and over the 
occipital lobe was opaque and thickened. 
The base of the brain presented the same changes in the leptomeninges. Arteries 
not atheromatous. The gyri and sulci normal. The brain substance on cross section 
soft and oedematous. All over the cut surface numerous congested capillaries and a 
few small haemorrhages were visible. 
The ventricles were somewhat dilated ; the ependyma smooth and firm. The 
spinal dura mater appeared normal. The spinal canal contained much yellow-coloured 
cerebro-spinal fluid in which were found numerous leucocytes and a few 
trypanosomes. The anterior and posterior spinal arteries with their corresponding 
veins could be followed as thick cords along the spinal cord and even traced to their 
last ramifications. 
On the anterior surface of the cord, on the right side, was a spindle-shaped dark 
red-stained mass (seven mm. in breadth) extending from the sixth cervical to the 
third dorsal, sharply defined and resembling a blood clot (Fig. 4). The cauda equina 
was embedded in gelatinous tissue. On cross-section the central canal was dilated ; 
the structure of the cord was well preserved ; the vessels in the grey substance and 
