8o THOMPSON YATES AND JOHNSTON LABORATORIES REPORT 
proliferated. The vessels are generally very much congested, and show a 
thickening ot the intiina. The perivascular infiltration often seems to compress the 
vessels. 
The nerve fibres show little degeneration, and that mostly around the 
infiltrated vessels. 
The large nerve cells of the brain and cord are greatly altered. The changes 
occur in nearly all groups. Somewhat irregularly distributed side by side with 
normal cells are others which do not contain any Nissl bodies, and appear 
disintegrated into a dust-like mass. Sometimes only a peripheral zone of Nissl bodies 
remains, at other times they are only present in the centre so that all stages of chroma- 
tolysis are seen. Often the nucleus is well preserved, at other times it is not distinguish- 
able at all. Irregular, fragmented cells are met with, their processes seeming to have 
been broken off. Their protoplasm, especially of the cells of the anterior cornua, is 
often quite filled with small vacuoles. 
The spinal ganglia sometimes show the same small-celled infiltration around the 
vessels as in the nervous centre. Small haemorrhages are found here and there. 
Many of the peripheral nerves were also examined. Some, such as the sciatic 
and median, appeared normal; others, for instance, some branches of the lumbar 
plexus, vagus, and others, showed a more or less pronounced small-celled infiltration 
of the peri- and endoneurium. 
Very many sections of all the organs were examined for bacteria with the above- 
mentioned methods, and, although very carefully searched, yet only a small number 
of large bacilli and large cocci which did not stain by Gram's method were seen. 
In the examination for trypanosomes in only a few sections of the brain, for example 
in the vessels of the choroid plexus, were a small number of trypanosomes found. 
C. — The Third Case, Boyo 
A black boy, fourteen years of age, died the 25th of May, at six p.m. The 
examination was not made until the 26th, at five p.m., twenty-three hours after 
death. 
Body was very emaciated with sunken orbits and temples and deeply indrawn 
intercostal spaces. On the soles of both feet were numerous ulcers caused by 
chiggers. The limbs were much wasted. Rigor mortis was marked. Over the 
sacrum was a superficial bed-sore, ten cm. in diameter. The skull was dolicho- 
cephalic, measuring fifty cm. at circumference. The dura mater very adherent to the 
skull, which was of normal thickness, having deep sulci for the vessels and numerous 
small depressions for the pacchionian bodies. The dura appeared normal, and its 
sinuses contained a fair amount of clotted blood. The surface of the brain was of 
normal configuration, the veins of the pia very congested and filled with dark clotted 
blood, and showed opaque white bands along the vessels and thickenings in places. 
