4 
5 
6 
Diagram of the first maiotic prophase in the Guinea pig, wherein only seven loops 
are represented : — 
[. Early spireme and chromatin centres at the ends of the loops. The chromatin 
centres are in groups of two and three. 
2. Synapsis. 
7,. Later phase where the chromatin centres have separated and one is breaking 
apart on the right. 
4. Later stage where the ends of the loops are all broken apart and the 
thread is split. 
5. Still later stage. 
6. — Final stage, the loops contracting to form the gemini (heterotype chromosomes). 
Several of the loops show the joint in their middle, representing the point 
of opposition of the two premaiotic chromosomes out of which each of the 
gemini is formed. 
