294 
PRODUCTION AND ABSORPTION OF I YMPH. 
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containing from 50 to 75 per cent, of dextrose, it will attract fluid from 
the tissues until its percentage 
is reduced to 5 or 6 per cent. ; 
that is to say, 45 c.c. of fluid 
containing 30 grms. of dextrose 
will attract water from the tissues 
until its total volume is increased 
to 500 c.c. Of course this esti- 
mate is merely a rough approxi- 
mation at the truth, since before 
the sugar has had time to attract 
all this fluid, a considerable 
amount of it will already have 
5 a ■ is *u ww i»™ .«>(» i e ft the vessels by diffusion. As 
Fig. 40. — Diagram to show the dilution ot the „ „ / a -. 
blood (i.e. hydremic plethora) produced in a matter of fact, however, we find 
dogs (Experiments 1, 2, 3, 4) by the injec- that injection of a strong solu- 
tion of 5 grms. dextrose per kilo, body- t i on of c | extrose [ & followed in a 
weight. The ordmates represent the . . • i i i 
volume of the blood (compared with the tew minutes by a considerable 
normal) as indicated by percentage of dilution of the blood, caused by 
haemoglobin. The abscissa represent inter- an mcrease i n its volume. Ill 
vals ot live minutes. The line AA, marks . £ t. i i 
the time at which the injection was finished some experiments of von Brasoi, 1 
in each experiment. The dotted lines to the volume of the circulating 
the left of AAj indicate the theoret Leal dilu- ] ,i oofl wag tlmg mcrease d to twice 
tion effected bv the volume ot liuid injected. ,, .. ., 
-After J. B. Leathes. or three times its previous 
amount ; and these observations 
have been fully confirmed in a series of careful experiments made by 
J. B. Leathes 2 (Fig. 40). 
As we should expect, 
this increase in the vol- 
ume of the circulating 
blood is attended by a 
large rise of capillary 
pressure in the abdomi- 
nal viscera (Fig 41), and 
we have here again to 
decide whether it is this 
rise of capillary pressure, 
or the change in the 
chemical composition of 
the blood, that determines 
the increased lymph flow. 
This question can be 
solved by using the same 
method that we adopted 
when dealing with the 
production of the in- 
creased lymph flow in 
bydrsemic plethora. We 
can entirely obviate the 
rise of capillary pressure 
if we bleed first to 300 
— 
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60 minutes 
Inj. of 40 grams dextrose 
Fig. 41. — To show influence of the intravenous injection 
of dextrose on the blood pressure in the abdominal 
viscera, and on the lymph now from the thoracic duet. 
The upper dotted line = pressure in portal vein. The 
lower dotted line = pressure in inferior vena cava. 
The thick continuous line = pressure in aorta. The 
thin continuous line = lymph flow. The ordinates 
represent venous pressure in centimetres of water, 
arterial pressure in centimetres Hg, and lymph How 
in cubic centimetres per ten minutes. 
c.c and then inject a concentrated solution 
1 Arch.f. Physiol., Leipzig, 1884, S. 211. 
-' Journ. Physiol., Cambridge and London, 189f), vol. xix. p. 1. 
