5 2 2 THE SALIVAR } ' GLANDS. 
stimulating the postganglionic chorda fibres, and by injecting pilo- 
carpine, was distinctly viscid, and more viscid than normal. The alveoli 
mentioned !>y Heidenhain were, I am inclined to think, the demilunes 
which a decrease in the size of the mucous cells inevitably brings into 
prominence, notwithstanding an actual decrease in the size of the 
individual demilune cells. 
Stimulation of the cervical sympathetic, during the progress of the 
paralytic secretion, has practically itsnormal action both in the dug and 
the cat. In the dog, it stives, when stimulated after a sufficient interval 
of rest, a brief quick flow of watery saliva, corresponding with the 
augmented secretion, and after this a slow slight secretion even thicker 
than usual. If the stimulus be prolonged, there is a long pause in the 
paralytic secretion, due partly to anaemia of the gland, and partly to the 
resistance offered to the flow by the thick saliva in the lumina and 
ducts, in the cat, the sympathetic produces secretion in the usual way 
and of the usual kind ; and unless the stimulation be too prolonged, the 
paralytic secretion slowly creeps on in the intervals between the several 
stimulations. 
Heidenhain noticed in the dog that section of the chorda tympani on 
one side caused a slight continuous secretion from the submaxillary 
gland of the opposite side. The occurrence of such a secretion I con- 
firmed in the cat. It is convenient to have a name for this secretion, 
and I have called it the antiparalytic, or, more briefly, the antilytic 
secretion. In my experiments the antilytic secretion was stopped by 
apncea and by excess of chloroform. Dyspnoea caused a secretion 
apparently greater than normal, though less than on the paralytic side. 
No certain antilytic secretion was observed either thirteen or forty-two 
days after section of the chorda. In its early stage, three days after 
section of the opposite chorda, it was diminished by cutting the chorda 
of the same side, and abolished by cutting the sympathetic also. So far, 
then, as regards the cat, there is some ground for thinking that the anti- 
lytic secretion is transitory and due to impulses set up in the central 
nervous system. 
Section of the chorda tympani probably leads to slow changes in the nerve- 
cells of the secretory centre which arc connected with the chorda fibres ; 
these changes might make the central nerve-cells more irritable, so that they 
passed into a condition of continuous slight activity, thus producing the anti- 
lytic secretion. Or the antilytic secretion might, as suggested by Bradford, be 
simply a reflex from the tissues injured during the section of the chorda. 
According to Heidenhain, the antilytic secretion in the dog continues after- 
section of both chorda tympani and sympathetic nerves. As it is difficult to 
see why the local mechanism should be so easily thrown out of gear, it is best 
to wait for further observations on the matter. 
Little is known as to the time taken for the chorda tympani fibres to 
regenerate. In a puppy, I obtained, three months after section of the chorda 
tympani, a secretion much as usual, on stimulating either the nerve which had 
been cut or the chordo-lingual, so that presumably regeneration is fairly com- 
plete in three months. 
Section of the cervical sympathetic 1 has no observable permanent effect 
upon the gland, and it causes no paralytic secretion. The blood vessels 
for a time dilate, but this soon passes off. The nerve soon loses its 
1 Cf. Langley, op. cit., and Bradford, op. fit. 
