A Study of the B. coli Group. 
329 
Thus the majority are referable to the A sub-group, which comprises all 
the "typical " B. coli varieties. Strains of iion-lactose-fermenters were also 
isolated, Al9, A34, A35 and A36 ; those of types 19, 34 and 35, however, 
developed lactose-fermenting variants in lactose medium {v. Table XXIX). 
Type A36 corresponded in cultural reactions to B. Morga7i No. 1 ; it was 
isolated in pure culture from a case of pyelitis and cystitis. 
In sub-group B, type 1 was of commonest occurrence, corresponding to 
MacConkey's type 'No. 74. The relative ])revalence of other varieties is 
shown in Table III. Among the organisms of sub-group B certain non-lactose- 
\ fermenters are also repi-esented, including 7 strains of " paracolon " types 
BlOl and B103. 
Patrick reported organisms of tliese types in cases of bacilluria occurring 
in the course of typhoid fever. They were present in such large numbers as 
to render the urine turbid. In primary culture they did not exhibit any gas 
production and therefore simulated B. typhosus in cultural reactions. I had 
the opportunity of examining his strains, and found them to be typical 
"paracolon" bacilli with the reactions shown (BlOl and 103) and similar to 
strains I had isolated from cases of urinary sepsis. 
Certain non-lactose-fermenters of the B sub-group were also noted which 
developed lactose-fermenting variants spontaneously in lactose media (B106 
and 107) {v. Table XXIX). 
Five inosite-fermenters (sub-group C) were isolated from urine, and 
8 strains referable to sub-group D. Four of the latter were non-lactose- 
fermenters ; 2 of these fermented only glucose, and, being non-motile, were 
therefore similar in cultural reactions to B. dysenteriae, Shiga. They were 
not, however, agglutinated by an anti-Shiga serum. One of these strains 
developed a lactose-fermenting variant. The characters of these strains are 
shown in Table V. 
Among the Gram-negative bacilH found in these cases of urinary sepsis B. 'proteus 
(Urobacillus liquefaciens septicus Krogius) was not infrequently noted, usually 
associated with £. coli or pyogenic cocci ; Gi-am-negative bacilli characterised by 
absence of carbohydrate fermentation have also been noted both in mixed and pure 
culture ; 4 strains of this type were isolated ; 2 were motile (corresponding to the 
typical B. faecalis alkaligenes) and 2 non-motile. 
Types Isolated from Faeces, Appendix Abscesses and other Sources. 
One hundred and eleven strains from specimens of faeces were analysed in 
the same way ; these were derived partly from normal specimens and also 
specimens submitted for bacteriological examination, e. g. for detection of 
B. typhosus. Their grouping was as follows : 
Sub-group A, 68. 
Sub-group B, 22. 
Sub-group C, 20. 
Sub-group D, 1. 
