Bemarks on Sojne Experiments with Snake-Venom. 
337 
Third rabbit. Accelerated respiration, discharge of white tears, saliva- 
tion, slight prolapsus vaginae, output of white urine, cramps, paralysis ; 
death after 25 minutes. Microscopical examination of the saliva : No 
leucocytes but small drops of a yellow liquid, like an oil. 
Post Mortem. — In all three rabbits : Haemorrhagic infiltration of the 
place of injection, blood thin somewhat hsemolytic ; no abnormalities in 
the internal organs. 
{b) Naia haie. Cobra. One drop of poison, dried out for 2 days, 
was redissolved in 2 c.c. normal saline solution and injected under the 
abdominal skin of a rabbit. 
Symptoms. — Uneasiness ; accelerated, sometimes jerky respiration for 
the first 15 minutes ; emission of urine. The animal then became quiet 
and died 35 minutes after injection without any additional symptoms. 
Post Mortem. — Blood dark ; heart in diastole ; ecchymoses on left 
endocardium, right endocardium normal ; lungs collapsed, oedematous ; 
haemoglobin-stained liquid in peritoneal cavity ; omentum, mesentery, and 
serous coat of small intestines injected. One Peyer's patch of coecum 
swollen and injected, other abdominal organs normal. Urinary bladder 
slightly injected, urine normal. Very likely the dose was not large 
enough to produce more distinct symptoms. 
4. SOLENOGLYPHA. 
(a) A specimen of Causus defiUppi — night-adder — was allowed to bite 
into the hind leg of a guinea-pig. The latter showed uneasiness and 
spasmodic respiration, but was normal again after an hour's time. 
A similar second experiment with both the same, snake and guinea- 
pig, was without result. The night-adder is known as a poisonous snake. 
(b) Bitis orietans. Puff-adder. The poison was squeezed out and 
1|- drops of it injected — 
1. Under the abdominal skin of a guinea-pig. 
^S^/mj^^oms.— Uneasiness, whimpers from time to time ; the animal 
was paralytic 2 hours after injection, and was found dead 5J hours 
later. 
Post Mortem. — Necrosis of the skin on the spot of the injection, diffuse 
dark red haemorrhagic infiltration of the skin and subcutaneous tissue and 
musculature of the abdomen. Blood thin, haemoly tic. Uterus pregnant ; 
uterine liquid, stained with haemoglobin. 
2. A rabbit was injected, like the guinea-pig, with 1*5 drops of the 
poison of the same puff-adder. Only local symptoms were seen, con- 
sisting in a necrosis of the skin where the injection had been made, 
about 3 cm. in diameter. The wound was not completely healed after 
12 days. 
