THE SWAMP FEVER OF HORSES. 
239 
of blood into the spleen, hemorrhages into the substance 
of organs were not seen. The internal lymphatic glands 
have usually been enlarged and much congested. Cloudy 
swelling of the heart muscle and of the kidneys, and, also, 
marked yellowish gelatinous edema of the pericardial fat 
were constantly seen. Pus, and other evidence of active 
inflammatory changes, occurred in none of our autopsies; 
the abscess on the chest of experimental Horse I. was due 
to a fall, and the fibrous tags which were found on the 
diaphragmatic surface of the liver of the same animal were 
of too long standing for them to have been due to a disease 
produced by the inoculation. 
The results of the microscopical examination of the organs 
were very constant. There has always been focal or central 
necrosis of the liver and a varying degree of acute paren- 
chymatous degeneration of the kidneys; blood pigment has 
been deposited in the lungs, spleen, liver and lymph glands 
and these organs have contained many phagocytic endothe- 
lial cells which had often taken up red blood cells. 
The ring bodies seen by us in the preparations of Ballah's 
Cases (IV. and V.) and reported by him (Annual Report of 
the Department of Agriculture of the Province of Saskatche- 
wan, 1907, 223-226) have also been seen by us, especially in 
Case I. (Black Gelding). Similar bodies have been found 
by us in the liver of a normal dog, which was incubated at 
27^ C. for four and a half hours before fixation in Zenker's 
fluid. They have also been seen in a case of liver necrosis 
in man, due to streptococcus infection. Our belief is that 
these bodies are formed by coagulation or precipitation of 
protein about droplets of soluble material. 
Sarcosporidia were found in all of the horses, while Scle- 
rostomum equinum or S. tetracanthum were almost always 
present. The liver lesions are of long duration and are evi- 
dently present throughout the course o^ the disease ; the 
kidney lesions, in one case at least, must be regarded as 
terminal. 
There is a marked anemia ; the red cells are greatly 
