226 
TODD AND WOLBACH. 
A. Horses. — Horse I. (Bay Gelding). — Weight, 1,656 pounds; age, 
8 (?) years. This horse had a very marked elephantoid condition of 
both legs, caused by a chronic lymphangitis ; possibly some of the irregu- 
larities of temperature may have been due to it. 
The animal was inoculated intraperitoneally on January 23d with 35 
cubic centimeters of pure blood taken from the Black Gelding (tempera- 
ture 96° F.) a few hours before its death. A week later the temperature 
rose to 102° F., and although it was irregular and fell daily, the tem- 
perature continued to rise during the whole of that week until it reached 
106.40 F. The temperature still remained irregular, but it fell gradually 
during the next week until it reached 99.4° F., when it again rose for five 
days and remained for three days between 104° and 105.5° F. The animal 
was now quite weak, and, during six weeks, the temperature usually 
remained between 100° and loP F. ; on two occasions it reached 102° F. 
On May 27th the horse was down and unable to rise. It was consequently 
killed in order that an autopsy might be performed. 
The pulse rate was usually low. With a temperature of 103.6° F. it 
was 48 ; just before death, with a temperature of 100.4° it was 32. 
During the course of the illness no edemas — other than the elephantoid 
condition mentioned — or other gross clinical signs were observed. The 
appetite always remained good and, until nine weeks before its death, the 
horse seemed to be as strong as ever. 
The following blood count was made on May 27, 1910, the day on 
which the animal was killed: red cells, 10,640,000; white cells, 29,500; 
hemoglobin, 115 per cent. 
Diflferential count: Polymorphonuclears, 85 per cent; lymphocytes, 
12.50 per cent; large mononuclears, 2 per cent; eosinophiles, .50 per cent 
— equals 100 per cent. 
Autopsy : (a) Gross appearances. — Both hind legs are greatly swollen 
and there is a large bruise, due to a fall, over the chest. On incision 
there is no subcutaneous fat ; the muscles are normal in appearance. 
There is a small amount of subcutaneous, yellowish edema over the bruise 
on the chest ; the muscles beneath this area are deep red and seem to 
contain extravasated blood. On cutting into the bruised mass small areas 
of pus, the size of millet grains, are found. 
The peritoneal and pleural cavities contain no free liquid. The peri- 
cardium contains about 100 cubic centimeters of clear, yellowish fluid. 
The heart, lungs, and bronchial lymph glands are normal. One or two 
of the lymph glands in the mediastinum are slightly enlarged, firm, and 
congested. 
On the under surface of the diaphragm there are a few small, old, 
fibrous tags. 
The spleen, liver, kidneys, and pancreas are normal in size and 
appearance. 
All the abdominal glands are normal in size and appearance with the 
exception of two from the mesentery and small gut, which are distinctly 
