222 
TODD AND WOLBACH. 
of Canada. Our thanks are due to Dr. Rutherford's Depart- 
ment for these animals and for financial assistance, which 
has assisted us in undertaking the investigations recorded in 
the present paper. The disease was diagnosed in both 
animals by Dr. McGilvray of Winnipeg. 
Case I. (Black Gelding). — Age about ro years; weight, 1,020 pounds; 
received January 19, 1910. This horse came from Oakville, Manitoba. 
It was first noticed to be ill during the latter part of June, 1909. It 
gradually became unfit for work, and it has been in its present condition 
for several weeks. 
Present condition : The horse is extremely weak, the gait is unsteady, 
and the weakness of the hind quarters is very marked. It is very thin 
and the abdomen is prominent and pendulous. The coat is very rough 
and seborrheic. The chest and the whole of the abdomen is edematous. 
No edema can be detected on the legs. The mucous membranes are pale. 
There are no petechial hemorrhages in the mouth, nostrils or eyes. The 
appetite for food and drink is excellent. Urine is frequently passed. 
Anemia is pronounced ; there are only 2,400,000 red cells to each cubic 
millimeter of blood, and only 20 per cent (two counts) of hemoglobin ; 
the hemoglobin was estimated with Sahli's hemoglobinometer. There is 
marked poikylocytosis and basophilia of the red cells. 
On the 20th of January the pulse rate was 72 and the temperature 
1020 F. From then until the 23d the temperature steadily fell. On 
January 23 the animal was in extremis and the temperature was 96° F. 
It was therefore killed and an autopsy wa^ made at once. 
Autopsy: (a) Gross appearances. — There is no subcutaneous fat. On 
the dependent side of the body the subcutaneous tissues are deep yellow, 
translucid, and edematous for a depth of one centimeter. The muscles 
are deep red, uniform and normal in appearance. 
There is no free liquid in the peritoneal cavity. On the liver and 
hepatic diaphragm, there are many fibrous tags, measuring from 8 to 12 
millimeters in length and 1.5 millimeters in diameter. In addition, there 
is a small area of strong, firm adhesions between the liver and the 
diaphragm. The lymph glands of the mesocolon are distinctly enlarged, 
edematous and hyperemic. Two peritoneal lymph glands lying near the 
kidney are also distinctly hyperemic; in these glands there are small 
white areas from one to three millimeters in diameter. The peribronchial 
lymph glands are normal. The lymph duct is much distended with a 
clear, pale, reddish fluid. 
The left pleura contains about a liter of slightly turbid fluid and there 
is a slight fibrous pleurisy. The right cavity contains no liquid or adhe- 
sions. The pericardial cavity contains about 300 cubic centimeters of 
clear fluid. 
