Dourine of Horses. 
9 
skin thickened. The testicles in some cases are soft and smaller than 
normal, while in others the opposite is found. Adhesions may be 
found between the different coverings of the testicles. In nearly all 
cases the scrotum is infiltrated. 
The lymphatic glands in the groin also are inflamed, and in many 
cases may be plainly visible as irregular, wavy lines under the skin. 
There is also a yellowish, gelatinous material beneath the skin in 
those areas where plaques were situated just before death. In cases 
of long duration there is more or less marked shrinkage of the 
muscular system, a condition naturally following the paralysis which 
Fig. 5. — Showing plaques. 
precedes death. Changes are noted in the brain, spinal cord, and 
spinal nerves, pointing to a degeneration of those parts, with an 
influx of fluid and formation of numerous hemorrhagic areas. The 
skeleton is also affected, and the bones may be softened. The bone 
marrow is congested, and hemorrhages and erosions may be seen on 
the articular cartilages of the joints. A discoloration of the joint 
fluid due to red blood cells is frequently seen, giving it a peculiar 
pinkish color. 
COURSE AND OUTCOME OF THE DISEASE. 
The course of the disease is extremely variable and may cover a 
long period of time. At the commencement of the attack the 
