278 
Notes on the Pigmentation of the Human Iris 
yellow in peripheral zone down and out. Left very similar. Twin with III. 27. III. 27, female, 
aet. 25. Twin with III. 26. Hair, brown. Eyes, blue, both with very faint spots of buff 
staining. III. 28, female, aet. 23. Hair, dark brown. Eyes, self light brown. Right has one 
1 mm. dark brown spot in peripheral zone down and out. Left ditto in pupillary zone upwards. 
III. 29, male, aet 20. Hair, once black has now a slight reddish tint. Eyes, light brown, 
uniform yellow-brown pigment layer, no rings. Left has one ^ mm. brown spot peripheral zone 
up and in. III. 30, female, aet. 16. Hair, brown. Eyes, light brown with darker pupillary 
circles. III. 31, male, aet. 14. Hair, dark brown. Eyes, light self-brown with one or two darker 
spots. IV. 1, male, aet. 12. Hair, light brown. Eyes, blue, no anterior pigment. IV. 2, 
female, aet. 10. Hair, light brown. Eyes, pale blue, very faint mottling of buff in sinuous 
lines. IV. 3, female, aet. 8. Hair, brown. Eyes, light brown with narrow pupillary circles 
of yellow-brown. IV. 4, female, aet. 5. Hair, light brown. Eyes, light brown, rather browner 
round pupils. IV. 5, female, aet. 3. Hair, light brown. Eyes, light brown, rather browner round 
pupils. IV. 6, female, aet. 2. Hair, light flaxen. Eyebrows and lashes the same — almost an 
albino. Eyes, pale blue, no anterior pigment. IV. 7, female, aet. 4^. Hair, light brown. Eyes, 
blue, no anterior pigment. IV. 8, male, aet. 9 mos. Hair, light brown. Eyes, blue, no anterior 
pigment. IV. 9, female, aet. 4. Hair, brown. Eyes, pale blue with indistinct buff pupillary 
circles and other buff dots here and there. IV. 10, female, aet. 2. Hair, brown. Eyes, blue, no 
anterior pigment. IV. 11, male, aet. 2. Hair, light brown. Eyes, blue, no anterior pigment. 
IV. 12, male, aet. 6. Hair, brown. Eyes, brown with darker pupillary circles. IV. 13, male, 
aet. 5. Hair, brown. Eyes, blue, no anterior pigment, a greyish white ring in peripheral zone. 
IV. 14, male, aet. 2. Hair, light brown. Eyes, blue, no anterior pigment. 
Fig. B. (March, 1910.) I. 1, male, aet. 33. Hair, brown. Eyes, blue, very faint stain of 
buff on upper part of each iris. I. 2, female, aet. 31. Hair, brown, used to be lighter. Eyes, 
very pale grey, almost white, no visible anterior pigment. By magnification the greyish-white 
colour of the iris is seen to be due to closely packed sinuous fibrous lines. II. 1, male, aet. 11. 
Hair, brown. Eyes, pale grey like the mother's, but with pupillary circles of yellow-brown, and 
one or two other ticks of the same colour here and there. II. 2, female, aet. 9. Hair, light 
brown. Eyes, dense pale grey all over except peripheral zones of blue, no visible anterior 
pigment. The grey irides very like the mother's, and quite as grey, verging on white. II. 3, male, 
aet. 8. Hair, brown. Eyes, the same pale grey, almost white irides but with median circles of 
yellowish-brown. II. 4, male, aet. 6. Hair, light brown. Eyes, pale blue, with faint pupillary 
circles of buff. II. 5, male, aet. 2. Hair, light flaxen. Eyes, blue, pupillary circles of grey, and 
other lines and spots of same, no visible anterior pigment. 
Fig. C. (Feb. 1911.) I. 1, male, aet. 43. Hair, medium brown. Eyes, blue with rather 
darker pupillary circles. Touched with one or two minute ticks of yellow-brown ; one brown 
pigment spot in Right periphery down and out of -25 mm. size, a smaller one up and out in 
median zone. I. 2, female, aet. 45. Hair, dark brown. Eyes, blue, no visible anterior pigment. 
II. 1, female, aet. 13. Hair, medium brown, rather reddish at tips. Eyes, blue. Right has a 
transverse heterochromic band formed by two distinctly red-brown patches of anterior jjigment, 
one at each side of pupil, the outer one 4^x 5| mm., widest at perijjhery, the inner one 3x4 mm., 
widest also at periphery. II. 2, female, aet. 11. Hair, red. Eyes, light blue, median irregular 
circles of reddish-yellow anterior pigment. II. 3, female, aet. 9. Hair, pale brown with reddish- 
golden tints. Eyes, pale blue with faintest possible staining of pale yellow in pupillary zones. 
Fig. D. (March, 1911.) 1. 1, male, aet. 37. Hair, used to be very fair, gradually got darker, 
now dark brown, almost black. Eyebrows and moustache light reddish brown, they have not 
altered. Eyes, bluish-grey with pale green tint in median and peripheral zones. Red complete 
pupillary rings, with rays stretching across median and peripheral zones. Refraction, § with 
manifest hypermetropia of -5 D. : probable total hypermetropia of 1-5 D. I. 2, female, aet. 38. 
Hair, medium brown, used to be very fair. Eyes, blue, yellow staining in patches, one in each 
eye, at upper and inner parts only. Greyish hazy spots form irregular peripheral circles. 
