340 Anomalies of Pigmentation among Natives of Nyasaland 
This child, who presents complete albinism of the skin and hair, shows the 
peripapillary orange-coloured network, but no trace of brown pigment in the iris. 
At the present time, in the absence of any opportunity for making a microscopical 
examination of irides, showing this condition, I am a little doubtful how such 
cases should be classed. I think it is quite possible that this colour network is 
not due to granular pigment at all, but is caused by diffuse pigment such as is 
found in many specimens of red and golden hair, as will be mentioned later. This 
child is therefore provisionally placed in Class I. 
Case C2. Saiti of Zomba. March, 1910. See Pedigree, Plate XXI, Fig. 1. 
The maternal grandmother is said to have been a light-skinned native (I 2). 
The mother's skin colour is light brown ; Bwauali (III 6) and William (III 5) 
are dark brown ; the first four children are dead and other members of the family 
were said to be of average colour, a dark brown. Saiti (III 7 on Plate XXI), 
aged seven, is practically the same colour as the back of the hand (not sunburnt) of 
a fair European, there are some blisters on the shoulders and arms but no freckles; 
skin thickened in places. The body and limbs are covered with fine whitish 
yellow hairs. Hair of head a dirty straw colour ; eyebrows and lashes thick and 
much curled. Eyes; lateral nystagmus present, day-blindness marked, irides 
bluish-grey, with a faint yellow pigment pattern; pupils black. With ophthal- 
moscopic mirror a red reflex shows through the pupil, but not through the iris. 
Fundus a light pink colour, possibly a little lighter than in the average European. 
Teeth very bad. Abdomen prominent, small umbilical hernia present. 
This boy is a very characteristic case of Class I, but shows the orange 
colouration in iris. 
The frequency with which albinos have body hair and also bad teeth will be 
mentioned later. The red reflex was here obtained and the fundus, though found 
to be even paler than in an average European, still contained enough pigment to 
prevent the choroidal vessels being seen. 
Case C 3. John of Mwandanas near Piupiu Hill, Zomba. January 6th, 1911. 
Mother and Father Anguru tribe. Pedigree, Plate XXI, Fig. 5. 
With the exception of the first child, which is said to have been white, all the 
other members of the family are known to have been averagely dark-skinned 
natives. An elder brother (III 3) was seen and found of average colour. 
John (Plate XIX (28)), aged 6 years, a complete albino. Skin colour that of 
a fair-skinned European; in places harsh and dry, smooth, with cracking and 
some blisters from sunburn. On the lower part of the abdomen, especially on the 
outer surfaces in front and on adjacent surfaces of thighs, numerous warts are 
present, mostly small, only slightly raised, and rather flat-topped. Others are 
larger, as is one situated over each clavicle, there are also a few which are filiform 
in character. They appear brownish in colour. The body and limbs are covered 
