H. S. Stannus 
359 
Class I Class II 
Class III 
Class IV 
Normal 
C2 CI 5 2 C'3 512 CI 
56 55 53 
A2 B6 
I B7 
j Mother 
.51 511 510 C9 B3 Cll (C13) (712 of normal 
59 012 
C8 
ClO 
Class I (a) C5 54" C4 
Partial A Ibinism 
Piebald 
As 
y Spotlings x 
a / b x c 
As 
Spotling 
As 
Spotling Leucoderma 
As As 
Leucoderma 
As 
Florence Bay Family Daus Girl H. Girl I. (hair tufts) (penis) of Ziemann ordinary type 
Coming to a more general discussion of the subject, among facts which have 
to be taken into consideration the following mentioned by Pearson are of great 
importance. Leucoderma may occur very early in life and become stationary. 
Pearson says " the possibility in Leucoderma of very early development followed 
by a stationary condition, and the fact that babies only gradually develop skin 
pigment so that congenital unpigmented areas may not be at once noticed, render 
it not so easy to distinguish partial albinism from stationary leucoderma in a 
European." Concentration of pigment in the neighbourhood of leucotic patches 
has been laid stress on as a feature of leucoderma, but it is not invariable. 
Symmetry and progressiveness and the combination of excess and deficiency are 
held by Crocker to be the characteristics of leucoderma, but as Pearson says 
"there can be little doubt that. . .leucoderma ceases to be progressive in some 
cases and that in such cases... the increased pigmentation at the borders is 
wanting." Further the symmetry " may be by no means marked " and the 
distribution of patches in undoubtedly congenital cases of leucosis may show a 
considerable degree of symmetry. Evidence of recovery of pigmentation in leuco- 
dermic patches is not wanting. 
Leucoderma has further been shown to be inherited, and a case due to 
Dr Joseph Jones has been published in which inherited leucoderma seems "to 
have culminated in albinism." There thus appears to be no criterion by which 
any case can be judged to be one of leucoderma or of partial albinism, and the 
history may yield the only facts of value. For these reasons, any hypothesis to 
explain albinism must explain at the same time the facts about leucoderma as 
they are known. 
4G— 2 
