Concluding Report on Pleuro-Pneumonia Experiments. 157 
it furnishes, and the excellence of the butter which the cream 
produces : — 
Composition of Butter made in accordance witJi Swartz's system. 
Water 13-26 
Cascine "92 
Pure butter fats 85-70 
Mineral matter (asli) -12 
100-00 
Augustus Voelckee, F.R.S. 
VIII. — Concluding Report on the Experiments at the Brown 
Institution on Pleiiro-Pneumonia. Bj J. Euedon-Sandekson, 
M.D., LL.D., F.R.S., late Superintendent of the Brown Insti- 
tution. With an Appendix by W. DuGUlD, Esq., M.R.C. V.S., 
late Veterinary Surgeon to the Institution. 
The inquiries which were undertaken in 1876, relating to the 
origin and nature of pleuro-pneumonia, and to the use of inocu- 
lation as a means of preventing its spread, having now been 
brought to a conclusion for the pi-esent, in consequence of the 
legislative difficulties which stand in the way of further experi- 
ment, I beg leave to submit to the Council the following state- 
ment of the results of our labours. 
The circumstances which led to the inquiry were set forth in 
a preliminary Report which was published in 1876. At that 
time no experiments had been made, but our first batch of 
experimental animals had been purchased, viz., two cows, two 
calves, and four other animals of different ages. They had 
been kept at Wandsworth Road for three months — a time which 
we considered sufficient, but not more than sufficient, to afford 
security against previous infection. I then stated that we should 
exclude any living source of infection from our premises, but 
would " try, in succession, every channel of mediate contagion 
known to us, using in our experiments all that deliberation and 
caution which the consideration of the importance and difficulty 
of the inquiry enforced upon us." 
Before proceeding with the narrative of our experiments it 
will, I think, be useful to state somewhat more fully than has 
hitherto been done, the nature of the practical questions which 
we have had in view, some of which have now assumed a greater 
importance than they had at the outset. Our objects have been 
(Ij to ascertain by experiment by what different ways a healthy 
animal can be infected ; (2) to ascertain whether inoculation is 
