Brown Institution on Pleiiro-Pneumonia. 
169 
resisted infection with foot-and-mouth disease on four occasions. With 
the exception of a cough (which was mostly heard in the morning or when 
disturbed after she had been lying for some time), she appeared in good 
health. The mean normal temperature obtained by daily observations extend- 
ing over several months was 100"8° Fahr., the range of the readings being 
from 100-1 to 101-7. 
About ihe middle of November for several days the temperature rose 
without any apparent cause, and again declined to the normal ; no other 
change in the animal's condition was noted. During the tirst 12 days of 
November the highest recorded tdmi)erature, that on the 12th, was 102"2, 
and the lowest, on the 10th, 101-2. 
Q'he daily record was as follows : — 
The temperature continued normal during the remainder of this month and 
the early part of December. 
Dec. 12, 1876. — Three fluid drachms of the exudation-liquid from pleuro- 
pneumonia lung were injected into the posterior auricular vein. 
Little local effect was produced for the first 15 days ; the animal showed 
no constitutional disturbance, the temperature being 101'73 Fahr., and the 
highest 102° Fahr. 
Dec. 28. — The 16th day the temperature rose to 103-2, but no other 
symptom was observed ; the pulse and respiration remained normal, and the 
cow fed and ruminated as usual. 
Dec. 29. — Still feeding and ruminating, but appears ill, breathing difiBcult 
and irregular, 30 per minute, pulse 60, temperature 105-6. Stands with head 
elevated and nose protruded, evinces no signs of pain when the intercostal 
spaces are pressed. 
Dec. 30. — Dull and prostrate, not feeding, constipation with mucous 
coating of fjeces; respirations 32, pulse 70, temperature 105-4. When moved, 
she grunts and shows some indication of jiain when the intercostal spaces 
are pressed. Auscultation does not reveal any lung consolidation. 
Dec. 31 — In same prostrate condition as yesterday, neither feeding nor 
ruminating, respirations 30, pulse 68, temperature 105*2. 
January 1, 1877. — Prostration increasing, losing condition rapidly, resj)i- 
ration 32, pulse 64, temperature 105-6. 
Jan. 2. — Respirations 36, pulse 70, weak, and temperature 105-6. 
Jan. 3, 9 a.m. — Respiration 60, and accompanied by a grunt, which proved, 
on examination, to be due to the closure of the glottis after each inspiration, the 
pulse was indistinct in the superficial vessels; temperature 104-8. At 3 p.m. 
on the same day tlie temperature had fallen to 104, and by 9 p.m. to 102-8 
— 2° in twelve hours. 
Jan. 4. — Lying, and unable to get up, breathing heavily, grunting, shivering, 
and grating her teeth ; respirations 82, pulse imperceptible, temperature 101-6 
in the morning, and only 100-4 at 10 p.m., when the animal was evidently 
sinking. 
Jan. 0. — Died about 7 a.m. Post-mortem 8 hours after death. With the 
exception of a small blood- clot under the capsule of the liver, the whole of the 
abdomiual viscera were healthy ; this small clot was recent, and probably due 
to a slight rupture in some of the animal's struggles to get up. 
The costal pleura on both sides showed numerous patches of recent exudation, 
the vicinity of which was studded with small hajmorrhagic spots, the surfaces 
of both lungs were smooth, and free from any adhesions to the sides of the chest, 
and from sub-pleural exudation, although on the surface of both there were some 
h»Qiorrha-ic patches. The right lung, from the animal having died on that 
Nov. 12.— 102-2 
„ 13.— 103-4 
„ 14.— 104-0 
Nov. 15.-103-8 
„ 16.-102-4 
„ 17.— 102-0 
