456 
Foot-and-Mouth Disease. 
most marked when the hind feet are attacked. As the disease 
advances the animal stands in an uneasy position, often shuffling 
its feet and moving with difficulty ; blisters appear between the 
claws and on the posterior part of the feet immediately above 
the hoofs, on the udder of milch cows, inside the lips, and on 
the tongue and palate. According to the severity of the attack 
will be the extent of these lesions ; in mild cases only the mouth 
may be affected, and that to a slight extent, or the feet may be 
attacked alone. Very seldom are the vesicles developed to an 
equal extent in all the positions mentioned, but in all cases 
there is a tendency to the separation of the epithelial and 
epidermoid covering of the mucous membrane and skin ; and it 
has been observed that the surface of the integument is de- 
squamated in the form of dried scales for some time after recovery. 
Sometimes a quantity of yellow curdy exudation is formed at the 
posterior part of the tongue and on the palate somewhat re- 
sembling the exudation in cattle-plague. A very remarkable 
specimen of this kind was taken from an Irish heifer which died 
of foot-and-mouth disease at Thirsk in 1867. A microscopic 
examination of this deposit proved it to be simple epithelial 
matter, as shown in the illustration No, 1. 
No. 1. 
Microscopic appearance of a mass of curdy exudation from the posterior part of the tongue of an Irish 
heifer which died of virulent foot-and-niouth_di6eaBe. Magnified 400 diameters. 
Soon after their appearance the vesicles become ruptured, 
and the contents, a clear limpid fluid, containing few organic 
