from an Agricultural and Veterinary Point of View. 109 
at Berlin. One-half the number were kept as test animals, 
and were not protectively inoculated. The second vaccination 
was made twelve days after the first, no ill effects following, 
except to six animals ; and the final test was applied to all the 
pigs, in another twelve days, either by inoculating them with 
the deadly virus, or by feeding them on food mixed with it. The 
experiment was as conclusive as that at Pouilly-le-Fort, with 
regard to anthrax. The pigs which had been protectively in- 
oculated were unaffected by the crucial test, while those not so 
indemnified nearly all succumbed to the natural or imposed 
infection. 
Rabies in animals is a disease which concerns people in 
general, from its terrible character when communicated to 
mankind as Hydrophobia ; but to agriculturists it possesses 
additional interest, because, in addition to the danger they 
personally incur, the losses they are liable to sustain among 
their stock from the bites of rabid dogs are by no means 
insignificant at times, in localities where the scourge prevails. 
Pasteur, busy in his laboratory investigating different diseases 
of the human species — typhoid fever, a serious bone-disorder, 
boils, puerperal fever in woman — in all of which he found 
special organisms, whose action he endeavoured to annul, 
applied himself more especially to the study of hydrophobia, 
which, for a long time, had occupied his mind. He had been 
particularly struck by the peculiar view entertained by many 
physicians, and others, that this fatal disease was largely, if not 
altogether, due to mental excitement, and that contagion had 
little if anything to do with it. Of course, these physicians were 
not acquainted with veterinary medicine, and had no experience 
of rabies in animals, else their imagination could not have so 
misled them. An opportunity occurred for him to collect some 
of the mucus from the throat of a child a few hours dead from 
the malady. With this he inoculated some rabbits beneath the 
skin, and they died in thirty-six hours ; their saliva conveyed 
the disorder to other rabbits. There was nothing at all novel 
in this, as rabbits had been infected through experimental 
inoculation years before. But death had been so rapid in 
Pasteur's rabbits, that there was no time for them to have had 
the disease. More rabbits were inoculated, and in the blood 
and tissues of those dying and dead he found a special microbe, 
which was easily cultivated in sterile infusions, and produced 
death in other rabbits, reappearing in them. This organism 
was also discovered in the saliva of children suffering from 
other maladies, and was not therefore special to hydrophobia. 
Grown in successive cultivations at twelve hours' interval, 
its virulence remained undiminished ; but if allowed to 
