272 
Report on the Health of Animals of the Farm. 
of hay in her mouth, taking care to keep it there for a few 
minutes, and to have it well bruised between her teeth. In the 
short space of about forty hours she was found to be unwell, 
and on examination, vesicles had commenced to form upon her 
tongue and also between her digits. The disease took its usual 
course, and vesicles were early developed upon her teats. Having 
thus proved that the secretions from the mouth contained infect- 
ing material, I was induced to continue my experiments, and 
next resolved on ascertaining whether the milk contained similar 
material. 
Already I had seen on one of the farms I had visited some 
pigs suffering from the malady, and fortunately I had some, 
young pigs at hand, which were at an age fit to take from the 
sow. They were divided into two lots, one of which was re- 
moved and put into a place of security, as far as possible from 
all other animals. Here they were kept without food for a few 
hours, and then some warm milk from the experimentally diseased 
cow was given them. This they eagerly partook of, consuming 
probably about a pint each. Subsequently they were fed on meal 
and milk from a healthy source, the same as supplied to the other 
moiety of the litter. Between fifty and sixty hours afterwards 
every one of the experimental pigs was suffering from the disease. 
I had now proof, by direct experiment, that the lacteal secretion 
was also impregnated with the materies morbi of the disease, 
and that by its use the malady could be communicated from 
animal to animal. The strictest sequestration of the diseased 
animals was observed, not only during their illness, but for 
some time afterwards, by Avhich means every other cow and pig 
on the premises escaped an attack. 
My next experiments were of a different order, and attended 
with a different result, which, however, is not without its value. 
In examining some cows on a farm, three or four miles distant 
from Twickenham, I observed on the teats of two or three of 
them some remarkably large vesicles, which were filled with a 
yellow-coloured and transparent fluid, apparently having the 
characters of ordinary serum. This I collected, and with care 
obtained nearly a tea-spoonful. Arriving at home, I inoculated 
a healthy cow with this fluid, taking all the precautions ^which I 
had done previously as to sequestration. The animal was care- 
fully watched, but no ill effects followed. The experiment was 
subsequently repeated, and again with a negative result. I may 
conclude this description of my original experiments, by remark- 
ing that I had thus early established facts in relation to the 
pathology of foot-and-mouth disease which years of subsequent 
experience have only tended to confirm. 
By the natural spread of the malady, many cattlej sheep, and 
