452 
Report of Experimental Work on Protective 
lent type occurred at Chelmsford, in which 46 adult cattle died 
within a few hours. Being personally engaged in the investiga- 
tion of this matter, we selected some material from a case most 
rapidly fatal. The same night we injected 30 drops of a mixture 
of spleen pulp and distilled water into the remaining ox, which 
had been " protected " with Pasteur's vaccine. Beyond the fact 
that the temperature rose on the following day to 106° F., and 
a little swelling at the point of inoculation, there was nothing 
worthy of remark till February 13th, when an abscess was 
noticed at the seat of previous swelling. This became very 
large — much pus escaping on its being opened. There was no 
bovine or other large susceptible animal at hand which could be 
used as a control. A rabbit, however, subjected to the same test 
showed much swelling at seat of inoculation, and died of typical 
anthrax in 78 hours. 
The foregoing cannot be regarded as absolute and in itself 
sufficient proof of the protective power of M. Pasteur's vaccine, 
though whatever demonstration there may exist, it is certainly 
favourable to it. 
Taking into consideration the expressed desire of the Vete- 
rinary Committee of the Society, and the means at our dis- 
posal, it was deemed unadvisable to prosecute this matter 
farther. 
The apparatus essential to the production of the " vaccine " 
by Pasteur's method is now in working order at the College, 
and can be utilized for the purpose at the Society's pleasure ; 
but in view of the limited nature of outbreaks of the disease in 
Great Britain, it will in all probability be more economical to 
obtain the necessary protective material direct from M. Pasteur's 
laboratory in Paris, should such be required. 
The disease technically known as " Symptomatic Anthrax," 
" Charbon Symptomatique," &c., has in different localities in 
this country received various appellations, as " Quarter 111," 
" Black Quarter," " Black Leg," "Strike," " Felling," " Irons," 
" Puck," &c., most of which are in some way significant of its 
more manifest characteristics. Its distribution throughout 
Great Britain is general, and the national loss from its ravages 
considerable. On many farms the annual average has been 
computed at from 5 to 10 per cent. Essentially a malady of 
young stock (here, at least, particularly cattle), its effects are most 
marked in breeding and rearing districts. 
Its more prominent features may be summarized as follows : — 
Its ordinary subjects are young cattle with ages ranging from six 
months to two years. Animals above and below this age seem to 
enjoy a large share of immunity. The attack is sudden, and 
the course usually rapid and fatal. Lameness and crepitating 
