Report on the Pathological Anatomy of Pleuro-pneumonia. 195 
The chief points of importance concerning the bronchi and 
vessels may be thus briefly summed up : — 
1. The bronchial tubes are always diseased in the region 
affected with the opaque conical form of consolidation and in its 
immediate vicinity. 
2. The mucous membrane is extensively diseased, the epi- 
thelium destroyed, and the bronchus filled with a plug. 
3. In this region also the walls of the bronchus are thickened, 
and its calibre is diminished. 
4. The sheath common to the broncho-vascular system is 
throughout swollen, rigid, and densely Infiltrated. 
5. The lymphatics of the entire vascular territory are rendered 
impervious by dense exudation. 
6. In the early stages of the affection, the morbid process of 
the lining of the bronchus is more extensive than that of its 
wall and surrounding tissue. 
7. The walls of the vessels may be implicated and their lining 
membrane irritated and damaged. 
8. Thrombosis may occur at one or several points of the 
vessels, and cause the occlusion of some of them. 
9. Small emboli may break off from a thrombus, and plug 
several brandies of the artery. 
10. The disease seems always to make greater progress in 
and around the bronchus than around the corresponding vessels. 
Conclusion. 
In the foregoing pages I have attempted to adhere to a plain 
statement of facts, as supplied by the notes of the autopsies 
taken on the spot, and by the examination of numerous specimens 
which have been sent to my laboratory. I have tried to avoid 
any expressions which involve theories, and have done little to 
work out the course of the very interesting morbid changes 
Avhich form the essence of this disease. Without some effort, 
however, to follow the order in which the various pathological 
events occur, the description of the appearances would be barren 
of interest or utility. I shall therefore now trv to trace the 
sequence of the morbid processes ; thus the order in which they 
occur may be ascertained, and possibly the initial stages of the 
affection arrived at. 
As may be seen from the brief summary of the views held 
on this subject, which was given in the beginning of this paper, 
it seems generally agreed that the pleura, or the sub-pleural 
and interlobular tissue, is the part first attacked. Although I 
commenced work with this idea firmly fixed in my mind, 
I cannot make my observations coincide with such a view, 
O 2 
