94 
HUMULUS LUPULUS. 
accustomed to prescribe. Pretty extensive observation has confirmed 
my former opinion, that diseases which are the consequence of 
exhai^^ted excitability, or more directly of a deranged state of the 
stomach and bowels, are certainly much relieved by this medicine. 
It frequently induces sleep and quiets nervous irritation, without 
causing costiveness, or impairing, like opium, the tone of the 
stomach, and merely increasing primary disease. The preparation 
most commonly used in this city is the tincture prepared by digesting 
3ij of the Lupulin, in 3j of alcohol; dose from 3i to Sij. Inquietude 
and watchfulness, connected with excessive irritabilitv, in all its 
gradations, from the restlessness consequent upi)n exhaustion and 
fatigue, to the most uncontrollable paroxysm of delirium tremens, 
are more frequently allayed by this remedy than any other in 
ordinary use." Dr. A. T. Thomson says, " But our own experience 
has not atForded us sufficient proof of its utility as a sedative; and 
Dr. Bigby's* experiments have lessened very much the confidence 
practitioners were disposed to give it." 
As an external application the decoction of hops has been used 
with some benefit, as a fomentation in painful swelliriiis and tumours. 
An ointment, formed of hops, (finely powdered) mixed up with lard, 
was recommended by the late Mr. Freake as an anodyne application 
to cancerous ulcers. 
Hops are given in the form of infusion, powder, tincture, or 
extract.f The infusion is made with from half an ounce to one 
ounce of hops to one pint of boiling water, the dose of which may 
be from one to two ounces twice or thrice a day : dose of the 
powder from five to twenty grains ; dose of the tincture from half 
a drachm to two drachms. 
The following preparations of Lupuline we consider to be more 
powerful and certain in their effects, than the above preparation of 
the hop itself. 
Pulvis Lupulince (Powder of Lupuline.) 
Take of Lupuline one part. 
White Sugar, powdered, two parts. 
First powder the Lupuline in a porcelain mortar, and afterwards 
add by degrees the sugar : mix them accurately. 
• -Vide London Medical Repository, vol. v. p. 97. 
+ This last preparation requires great care in preparing, otherwise it becomes 
inert.— JEd. 
