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Aneemia in Sheep, knoivn also by the terms 
to the lessening of the entire volume of the blood, there is 
deficiency of the red-blood globules and of the essential colour- 
ing material, together with certain unnatural conditions in the 
plasma, or liquid material. 
Water may be in excess, or the proportion of the albuminous 
constituents or of the salts may be diminished. It is chiefly to 
the lessening in amount of these two main elements of the blood, 
the formed or the globules, and the plastic or albuminous, that 
the serious consequences of ana?mia are traceable. Every vital 
function being dependent for its maintenance upon the due 
supply and interchange of oxygen in the body, any deficiency of 
the red-blood globules cannot long exist without extensively dis- 
tributed and serious interference with every animal function. 
Every nutritive and secretory action becomes more or less 
interfered with. Growth, development, stability of tissue, and 
dynamic action are impaired. Respiration and circulation are 
disturbed, while the entire phenomena connected with digestion 
and assimilation are perverted ; producing, as the result, a steady 
increase of the blood contamination from imperfect oxidation, 
and the production of unnatural and noxious materials or com- 
pounds. Whether occurring from want or waste, the absence from 
the blood of the albuminous compounds so often found in ana?mia 
cannot long exist alone. Upon their existence in correct pro- 
portion in the blood depends, not merely the opportunity of 
nourishment being afforded to the several extra-vascular tissues, 
but also to the oxidizing agents themselves, the red globules. 
With deficiency of the albumens these latter will not long remain 
in a healthy condition or proportion. Being dependent for their 
life and development on the support derived from the albumens, 
an absence of these is shortly followed by changes in the formed 
materials, and a state of aglobulism is added to that of a 
deficiency of the albumens. 
Causation. — Various and somewhat different agencies are found 
to operate in the production of aneemia as a diseased condition, 
the chief of these being a deficient supply of blood or of blood- 
forming materials, excessive waste of these, or a combination of 
both classes of factors. With sheep, there is rarely any specially 
noted disease of such organs as are particularly concerned in the 
manufacture or distribution of blood, as the lymphatic or blood- 
glands, or the various conduits by which it is conveyed in its 
course through the body ; neither does the serious disturbance 
seem to be attached to such general unhealthy states as are 
recognised in tuberculosis, or allied conditions representing 
abnormal formative processes. The greater number of the cases 
are what may be designated primary anaemia, where all that may 
be asserted is that there exists a want of relative balance between 
