Prevention of Splenic Fever, Sfc, at the Brown Institution. 285 
Experiment V. 
Day of 
Observa- 
tion, 
Rectal Temperature. 
Kemaieks. 
IMoming. 
Noon. 
Evening. 
1 
101- 
101- 
2 
101- 
101- 
Fifth inoculation, direct from sheep» 
3 
103-4 
103-4 
104- 
4 
101- 
100-8 
101-4 
5 
101-6 
101-6 
6 
101-2 
101-6 
7 
100-4 
101- 
8 
100-4 
Case II. — The material used for these experiments was derived 
from a case of anthrax in a horse, the poison having been trans- 
mitted successively through two guinea-pigs. The preparation 
of the material has already been described (part having been 
used for Inoculation 3 in Case I.). 
The other part of the fluid was injected subcutaneously in an 
old emaciated cow, which, as was discovered subsequently, was- 
in-calf. 
On the day of inoculation no symptoms occurred. On the 
following day the temperature rose to 102*4° morning, 103''^ 
evening. On the third day the morning temperature was 103"6°, 
evening 102-4°, but there was no loss of appetite, nor were any 
other symptoms noticed. On the morning of the fourth day 
the animal was found dead. 
Case II. 
Day of 
Observa- 
tion. 
Temperature in Rectum. 
Morning. 
Noon. 
Evening. 
1 
2 
3 
4 
101- 4 
102- 4 
103- 6 
Found dead. 
10°l-4 
(Inoculation). 
102- 
102- 
10°l-6 
103- 
102-4 
Post-mortem (6 to 9 hours after death). Body emaciated. A 
bloody mucous discharge flowed from nostrils and anus. 
Stomach full and healthy. Intestines congested, with bloody 
extravasation here and there. Spleen somewhat enlarged, 
weighing 2 lbs. 14 oz., presents haemorrhagic spots in the capsule. 
On section, tissue highly vascular, somewhat soft but not diffluent. 
Liver and kidneys apparently healthy. 
