Prevention of Splenic Fever, S^c, at the Brown Institution. 289 
Liver small but natural. 
Sploen somewhat enlarged and soft ; on section, however, not 
pulpy, though readily broken down. 
Kidneys somewhat swollen and soft, but otherwise of natural 
appearance. 
Stomach and intestines natural. 
Brain and cord appear perfectly healthy. 
On microscopic examination the blood was found to contain 
very long rods in comparatively small proportion, i.e., though 
several were seen in each field, there was no crowding of them 
together as is often the case. But the rods were of enormous 
length, many reaching almost the entire width of the field, 
measuring from "05 to 'llh of a millimetre in length, or nearly 
twenty times the usual length, having, in fact, an appearance 
often found in the bacilli under cultivation, but rarely in the 
body. 
In the bronchial and tracheal mucus, and in the bloody fluid 
exuding from the lungs, similar elongated Bacilli were found. 
In the spleen, repeated examination by myself and Mr. 
Banham, both of the splenic tissue and of the bloody fluid 
exuding from it, entirely failed to discover any Bacilli. Only 
a few ordinary micrococci were observed, not a single Bacillus 
in any of the specimens examined. 
Microscopic examination of the lungs after hardening in 
chromic acid, showed that these scattered spots were actual 
haemorrhages. In addition were seen the usual appearances ; 
Bacilli in the capillaries and terminal arteries of the pulmonary 
system, and also in the interlobular connective tissue. 
Day of 
Inocula- 
tion. 
Temperatures. 
Morning. 
Evening. 
o 
o 
1 
lOi 
2 
101-6 
103- 
3 
102- 
102-4 
4 
102-6 
103-2 
5 
103- 
107- 
6 
Found dead. 
I have already described the result of the inoculation of a steer 
(which had been previously inoculated with cultivated virus 
from a guinea-pig) with blood from this case. The results pro- 
duced on the sheep are a striking proof of the virulence of the 
material after successive cultivations. 
To summarise the results of these experiments ; — 
VOL. XVI. — S. S. U 
