Prevention of Splenic Fever, &,-c., at the Brown Institution. 297 
the muscles. The muscles themselves are of blackish-red colour, 
mottled with points of ecchjmosis, and there is a similar oedema 
of the connective tissue between the bundles of muscular fibres^ 
which separates the individual bundles, in a manner analogous 
to that in which the exudation in the lung in pleuro-pneumonia 
of cattle separates the pulmonary lobules. 
The diseased quarter is said to be very deadly to pigs and 
dogs, and it occasionally happens that men who dress the car- 
cass, if scratched, die very rapidly with a peculiar form of blood- 
poisoning ; yet it is stated to be a common practice to cut ofT 
and bury the affected quarter, and to cook and eat the rest, 
without any known ill-effects. 
By some authors * the disease is divided into two forms, the 
one affecting the quarter, the other chiefly involving the intes- 
tines. In the latter form the chief symptoms are the passage of 
bloody faeces with tenesmus, occasionally, also, the urine being 
bloody ; great tympanitic distension of the abdomen, and rapid 
prostration. The mucous membrane of the intestines is greatly 
swollen and intensely congested, or almost gangrenous ; they 
contain soft bloody fa'ces. This is most marked in the large 
intestine. The mesenteric glands are greatly swollen, con- 
gested, and softened, and contain ha?morrhagic spots. There 
may be bloody exudation in the peritoneum. 
This form of the disease appears to be somewhat allied to the 
so-called Mijcosis intestinalis. 
It may be well here to point out certain features in which the 
disease usually differs from splenic apoplexy. 
1. Its limitation to certain localities and certain periods of the 
year, and the apparent absence of direct contagion in most cases. 
2. The gangrenous emphysematous nature of the swellings, 
which is not usual even with local forms of anthrax. 
3. The general course and long duration of the disease in 
some cases. 
4. The presence of coma and convulsions for some time 
before death. 
5. The absence of swelling of the spleen. 
G. So far as most observations go, the absence of the charac- 
teristic anthrax Bacillus from the blood. 
And, as I shall further show, the disease may be exactly 
reproduced in rodents by inoculation from various parts of the 
body, without the discoverable presence of anthrax Bacillus in 
the blood or organs of the inoculated animals. 
On the other hand, in no inoculation have I succeeded in 
* A full account of these diseases is given by F. Hable in the ' Oesterreichische 
Vierteljahreschrift fiir Wissen. Yeterinarkunde.' Bd. li. H. 1, which has been 
translated by Mr. Banham. 
