candidate human hematopoietic stem-cell popula- 
tion. Proc Natl Acad Sci USA 89:2804-2808. 
Griffiths, G.M., Alpert, S., Lambert, E., McGuire, J., 
and Weissman, I.L. 1992. Perforin and granzyme 
A expression identifying cytolytic lymphocytes in 
rheumatoid arthritis. Proc Natl Acad Sci USA 
89-.549-553. 
Heimfeld, S., Hudak, S., Weissman, I.L., and Ren- 
nick, D. 1991. The in vitro response of phenotyp- 
ically defined mouse stem cells and myeloeryth- 
roid progenitors to single or multiple growth 
factors. Proc Natl Acad Sci USA 88:9902-9906. 
Heimfeld, S., and Weissman, I.L. 1991. Develop- 
ment of mouse hematopoietic lineages. Curr Top 
Dev Biol 25:155-175. 
Heimfeld, S., and Weissman, I.L. 1992. Character- 
ization of several classes of mouse hematopoietic 
progenitor cells. Curr Top Microbiol Immunol 
177:95-105. 
Hu, M.C -T., Crovi^e, D.T., Weissman, I.L., and 
Holzmann, B. 1992. Cloning and expression of 
mouse integrin jSp (|87): a functional role in 
Peyer's patch-specific lymphocyte homing. Proc 
Natl Acad Sci USA 89:8254-8258. 
Ikuta, K., Ingolia, D.E., Friedman, J., Heimfeld, S., 
and Weissman, I.L. 1991- Mouse hematopoietic 
stem cells and the interaction of c-kit receptor 
and steel factor. Int J Cell Cloning 9:451-460. 
Ikuta, K., Kina, T., MacNeil, I., Uchida, N., Peauh, 
B. , Chien, Y.-H. , and Weissman, I.L. 1992. Devel- 
opment of 76 T cell subsets from fetal hematopoi- 
etic stem ceils. Ann NY Acad Sci 651:21-32. 
Ikuta, K., Uchida, N., Friedman, J., and Weissman, 
I.L. 1992. Lymphocyte development from stem 
cells. Annu Rev Immunol 10:759-783. 
Ikuta, K. , and Weissman, I.L. 1991. The junctional 
modifications of a T cell receptor 7 chain are de- 
termined at the level of thymic precursors. /ii'xp 
Med 174:1279-1282. 
Ikuta, K., and Weissman, I.L. 1992. Evidence that 
hematopoietic stem cells express mouse c-kit but 
do not depend on steel factor for their generation. 
Proc Natl Acad Sci USA 89:1502-1506. 
Lagasse, E., and Weissman, I.L. 1992. Mouse MRP8 
and MRP14, two intracellular calcium-binding 
proteins associated with the development of the 
myeloid lineage. Bloodl^■A^Ql -Wb . 
Lieberman, M., Hansteen, G.A., Waller, E.K., Weiss- 
man, I.L., and Sen-Majumdar, A. 1992. Unex- 
pected effects of the severe combined immunode- 
ficiency mutation on murine lymphomagenesis./ 
Exp Med 176:399-405. 
Negrin, R.S., and Weissman, I.L. 1992. Hematopoi- 
etic stem cells in normal and malignant states. 
Marrow Transplant Rev 2:23-26. 
Neuhaus, H., Hu, M.C.-T., Hemler, M.E., Takada, Y., 
Holzmann, B., and Weissman, I.L. 1991- Clon- 
ing and expression of cDNAs for the a subunit of 
the murine lymphocyte-Peyer's patch adhesion 
molecule. / Cell Biol 115:1149-1158. 
Peault, B., Weissman, I.L., Baum, C, McCune, J.M., 
and Tsukamoto, A. 1991 Lymphoid reconstitu- 
tion of the human fetal thymus in SCID mice with 
CD34+ precursor cells. / Exp Med 174:1283- 
1286. 
Rinkevich, B., Lauzon, R.J., Brown, B.W.M., and 
Weissman, I.L. 1992. Evidence for a pro- 
grammed life span in a colonial protochordate. 
Proc Natl Acad Sci USA 89:3546-3550. 
Rinkevich, B., and Weissman, I.L. 1991. Interpop- 
ulational allogeneic reactions in the colonial pro- 
tochordate Botryllus schlosseri. Int Immunol 
3:1265-1272. 
Rinkevich, B., and Weissman, I.L. 1992. Alloge- 
neic resorption in colonial protochordates: con- 
sequences of nonself recognition. Dev Comp Im- 
munol 16:275-286. 
Rinkevich, B., and Weissman, I.L. 1992. Chimeras 
vs genetically homogeneous individuals: poten- 
tial fitness costs and benefits. Oikos 63:1 19-124. 
Rinkevich, B., and Weissman, I.L. 1992. Incidents 
of rejection and indifference in Fu/HC incompati- 
ble protochordate colonies. /ijjcp Zool 263:105- 
111. 
Spangrude, G.J., Smith, L., Uchida, N., Ikuta, K., 
Heimfeld, S., Friedman, J., and Weissman, I.L. 
1991. Mouse hematopoietic stem cells. Blood 
78:1395-1402. 
Uchida, N., and Weissman, I.L. 1992. Searchingfor 
hematopoietic stem cells: evidence that Thy- 1 . 1 
Lin" Sea- 1 ^ cells are the only stem cells in C57BL/ 
Ka-Thy-1.1 bone m?LVvow. J Exp Med 175:175- 
184. 
Vaux, D.L., Aguila, H.L., and Weissman, I.L. 1992. 
Bcl-2 prevents death of factor-deprived cells but 
fails to prevent apoptosis in targets of cell- 
mediated killing. Int Immunol 4:821-824. 
Waller, E.K., Kamel, O.W., Cleary, M.L., Sen-Majum- 
dar, A., Shick, M.R., Lieberman, M., and Weiss- 
man, I.L. 1991. Growth of primary T-cell 
non-Hodgkin's lymphomata in SCID-hu mice: re- 
quirement for a human lymphoid microenvi- 
ronment. 5/oo<3? 78:2650-2665. 
Wood, G.S., Dubiel, C, Mueller, C, Abel, E.A., 
Hoppe, R.T., Edinger, A., Weissman, I.L., and 
Warnke, R.A. 1991. Most CD8+ cells in skin le- 
sions of CD3^CD4+ mycosis fungoides are CD3^ T 
cells that lack CDllb, CD16, CD56, CD57, and 
human Hanukkah factor mRNA. Am J Pathol 
138:1545-1552. 
IMMUNOLOGY 369 
