254. Clark, D.V., and Henikofif, S. 1992. Unusual organizational features of the Drosophila Gart locus are not conserved within 
Diptera . / Mol fro/ 3 5 : 5 1 - 5 9 . 
255. Clark, S.G., Stern, M.J., and Horvitz, H.R. 1992. C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 
domains. Nature 356:340-344. 
256. Clarke, M., Dominguez, N., Yuen, I.S., and Gomer, R.H. 1992. Growing and starving Dictyostelium cells produce distinct 
density-sensing factors. Dev Biol 152:403-406. 
257. Clarke, N.D., Beamer, L.J., Goldberg, H.R., Berkower, C, and Pabo, CO. 1991 . The DNA binding arm of X repressor: critical 
contacts from a flexible region. Science 254:267-270. 
258. Claxton, D., Suh, S.-P., Filaccio, M., Ellerson, D., Gaozza, E., Anderson, B., Brenner, M., Reading, C, Feinberg, A., Moen, R., 
Belmont, J., Moore, K., Talpaz, M., Kantarjian, H., and Deisseroth, A. 1991. Molecular analysis of retroviral transduction in 
chronic myelogenous leukemia. Hum Gene Ther 2:317-321. 
259. Clemens, P R., Fenwick, R.G., Chamberlain, J.S., Gibbs, R.A., de Andrade, M., Chakraborty, R., and Caskey, C.T. 1991. Carrier 
detection and prenatal diagnosis in Duchenne and Becker muscular dystrophy families, using dinucleotide repeat 
polymorphisms. Am J Hum Genet 49.951-960. 
260. Clipstone, N.A., and Crabtree, G.R. 1992. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. 
Nature 357:695-697. 
261. Cogen, P.H., Daneshvar, L., Metzger, A.K., Duyk, G., Edwards, M.S.B., and Sheffield, V.C. 1992. Involvement of multiple 
chromosome 17p loci in medulloblastoma tumorigenesis. Am J Hum Genet 50:584-589. 
262. Cohen, B., McGuilin, M.E., Pfeifle, C, Segal, D., and Cohen, S.M. 1992. apterous, a gene required for imaginal disc develop- 
ment in Drosophila encodes a member of the LIM family of developmental regulatory proteins. Genes Dev 6:71 5-729. 
263. Cole, W.G., Patterson, E., Bonadio, J., Campbell, P.E., and Fortune, D.W. 1992. The clinicopathological features of three babies 
with osteogenesis imperfecta resulting from the substitution of glycine by valine in the prowl (I) chain of type 1 procollagen./ 
Med Genet 29:1 12-1 18. 
264. Colin, S.F., Chang, H.-C, Mollner, S., Pfeuflfer, T., Reed, R.R., Duman, R.S., and Nestler, E.J. 1991. Chronic lithium regulates the 
expression of adenylate cyclase and Gj-protein a subunit in rat cerebral cortex. Proc Natl Acad Sci USA 88:10634-10637. 
265. Colley, N.J., Baker, E.K., Stamnes, M.A., and Zuker, C.S. 1991. The cyclophilin homolog ninaA is required in the secretory 
pathway. Ce// 67:255-263. 
266. Collins, F.S. 1991. Identification of disease genes: recent successes. Hosp Pract 26:93-98. 
267. Collins, F.S. 1991. Identification of the type 1 neurofibromatosis gene. Neurosci Forum 1:5. 
268. Collins, F.S. 1991. Medical and ethical consequences of the Human Genome Project. / Clin Ethics 2:260-267. 
269. Collins, F.S. 1991. Of needles and haystacks: finding human disease genes by positional cloning. Clin Res 39:615-623. 
270. Collins, F.S. 1992. Cystic fibrosis: molecular biology and therapeutic implications. Science 256:774-779. 
271. Collins, F.S. 1992. Physician-scientists: a vanishing breed, ya/e Afe</ Fall/Winter:5-8. 
272. Collins, F.S. 1992. Positional cloning: Let's not call it reverse anymore. Nature Genet 1:3-6. 
273. Collins, F.S., and lannuzzi, M.C. 1992. Genetic defect in cystic fibrosis. In Update: Pulmonary Diseases and Disorders 
(Fishman, A.P., Ed.). New York: McGraw-Hill, pp 83-92. 
274. Collins, F.S., and Wilson, J.M. 1992. Cystic fibrosis. A welcome animal model. Nature 358:708-709. 
275. Collins, S.,Altschmied, J., Mellon, P.L., Caron, M.G., and Lefkowitz, R.J. 1991. Multiple pathways regulate adrenergic receptor 
responsiveness. In Neurotransmitter Regulation of Gene Transcription (Costa, E., and Joh, T.H., Eds.). Washington, DC: 
Thieme, vol 7, pp 183-191. 
276. Collins, S., Caron, M.G., and Lefkowitz, R.J. 1992. From ligand binding to gene expression: new insights into the regulation of 
G protein-coupled receptors. Trends Biochem Sci 17:37-39. 
277. Collins, S., Lohse, M.J., O'Dowd, B., Caron, M.G., and Lefkowitz, R.J. 1991. Structure and regulation of G protein-coupled 
receptors: the /32-adrenergic receptor as a model. Vitam Horm 46:1-39. 
278. Comai, L., Tanese, N., and Tjian, R. 1992. The TATA-binding protein and associated factors are integral components of the RNA 
polymerase 1 transcription factor, SLl. Cell 68:965-976. 
279. Condron, B.G., Atkins, J. F., and Gesteland, R.F. 1991. Frameshifting in gene 10 of bacteriophage Tl . J Bacteriol 173:6998- 
7003. 
280. Condron, B.G., Gesteland, R.F., and Atkins J. F. 1991 . An analysis of sequences stimulating frameshifting in the decoding of gene 
10 of bacteriophage T7. Nucleic Acids Res 19:5607-561 2. 
281 . Connell, N., Stover, K., and Jacobs, W.R., Jr. 1992. Old microbes with new faces: molecular biology and design of new vaccines. 
Curr Opin Immunol 4:442-448. 
282. Conricode, K.M., Brewer, K.A., and Exton, J.H. 1992. Activation of phospholipase D by protein kinase C. Evidence for a 
phosphorylation-independent mechanism./ Biol Chem Zdl ■.1X99-7202. 
283. Consalez, G.G., Stayton, C.L., Freimer, N.B., Goonewardena, P., Brown, W.T., Gilliam, T.C., and Warren, S.T. 1992. Isolation 
and characterization of a highly polymorphic human locus (DXS455) in proximal Xq28. Genomics 12:710-714. 
284. Convit, J., Sampson, C, Zuniga, M., Smith, P.G., Plata, J., Silva, J., Molina, J., Pinardi, M.E., Bloom, B.R., and Salgado, A. 1992. 
Immunoprophylactic trial with combined Mycobacterium leprae/BCG vaccine against leprosy: preliminary results. Lancet 
339:446-450. 
