Contents 
65 Computational Structural Biology 
Axel T. Briinger, Ph.D. 
67 Biophysical Studies of Eukaryotic Gene Regulation and 
Molecular Recognition 
Stephen K. Burley, D.Phil., M.D. 
69 Molecular Studies of Ca^^ Channels and the 
Dystrophin- Glycoprotein Complex 
Kevin P. Campbell, Ph.D. 
71 Gene Targeting 
Mario R. Capecchi, Ph.D. 
73 Genetic Control of Segmentation and Segmental Pattern Formation 
in Drosophila 
Sean B. Carroll, Ph.D. 
75 Human Disease Gene Identification and Correction 
C. Thomas Caskey, M.D. 
77 Enzymatic RNA Molecules and the Structure of Chromosome Ends 
Thomas R. Cech, Ph.D. 
79 Molecular Genetics of Histocompatibility 
David D. Chaplin, M.D., Ph.D. 
81 Hormonal Regulation of Gene Expression 
William W. Chin, M.D. 
83 Technologies for Genome-sequencing Projects 
George M. Church, Ph.D. 
87 Molecular Genetics of Limb Development in Drosophila 
Stephen M. Cohen, Ph.D. 
89 Tracking Genes That Cause Human Disease 
Francis S. Collins, M.D., Ph.D. 
91 Development of the Immune System 
Max D. Cooper, M.D. 
93 Structure and Function of RNA Polymerase II 
Jeffry L. Corden, Ph.D. 
95 Mechanically Activated Ion Channels 
David P. Corey, Ph.D. 
97 Genetic Regulatory Mechanisms in Cellular Differentiation 
Gerald R. Crabtree, M.D. 
99 Regulation of Human Retroviral Gene Expression 
Bryan R. Cullen, Ph.D. 
V 
