Contents 
351 Generating a Repertoire of Antigen-Specific Receptors 
David G. Schatz, Ph.D. 
353 Intracellular Protein Transport 
Randy W. Schekman, Ph.D. 
355 Development and Function of the Synapse 
Richard H. Scheller, Ph.D. 
357 Molecular Pathogenicity Studies of Enteric Bacteria 
Gary K. Schoolnik, M.D. 
361 Three-Dimensional Structure of Eukaryotic Chromosomes 
John W. Sedat, Ph.D. 
363 A Molecular Basis of Familial Hypertrophic Cardiomyopathy 
Jonathan G. Seidman, Ph.D. 
367 Computational Neurobiology of Sensory Representations 
TerrenceJ. Sejnowski, Ph.D. 
369 Adenovirus as a Model for Control of Gene Expression 
Thomas E. Shenk, Ph.D. 
371 Growth Control of Myeloid Cells 
Charles J. Sherr, M.D., Ph.D. 
373 The Role of Second Messengers in Ion Channel Regulation 
Steven A. Siegelbaum, Ph.D. 
375 Chemistry of Cellular Regulation 
Paul B. Sigler, M.D., Ph.D. 
377 The Mitochondrial Genome of Trypanosomes 
Larry Simpson, Ph.D. 
379 Regulation of Gene Activity During B Cell Development 
Harinder Singh, Ph.D. 
381 Regulation of Gene Expression in Developing Lymphocytes 
Stephen T. Smale, Ph.D. 
383 Developmental Genetics 
Philippe M. Soriano, Ph.D., D.Sc. 
385 Understanding How Eggs Work 
Allan C. Spradling, Ph.D. 
387 Structural Studies of Regulatory Proteins 
Stephen R. Sprang, Ph.D. 
389 Insulin and the Islets of Langerhans 
Donald F. Steiner, M.D. 
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