Index 
Becker muscular dystrophy {continued ) 
molecular genetics, 233-234 
neuronal function, Ix 
Beckwith-Wiedemann syndrome (BWS), 131 
Betaglycan, transforming growth factor and, 275-276 
i3-turn, genetic analysis of, 140 
6«co/rf gene, transcription control, 112-114 
Binary probes, RNA replication, 509-510 
Biological clock, biochemical actions of, 465-466 
Bioph^ics, eukaryotic gene regulation, 59-60 
Bithorax complex 
Drosophila melanogaster, 349-350 
limb development genetics in Drosophila, 80 
Blazing a Genetic Trail, xix 
Blood-brain activators, host-pathogen interactions, 493-494 
Blood cells 
formation mechanisms, 445-446 
molecular genetics of, 305-306 
Blood clotting 
cell adhesion and, 195-196 
genetic regulation, 344-346 
molecular genetics, 161-162 
prevention mechanisms, 123-124 
Blood groups, glycosyltransferase molecular genetics and, 
267-268 
Blood vessels, paracrine control, 459-460 
Bone marrow 
blood cell formation, 445 
transplants, coagulation genetics, 162 
Borrelia burgdorferi, immune tolerance, 136-138 
Breast cancer, gene mapping techniques and, 82 
bride of sevenless (boss) gene, retinal cell-cell interactions, 
471-472 
C4b-binding protein (C4bBP), clotting prevention, 123- 124 
Cadherin, neuron development, 335-336 
Caenorhabditis elegans 
developmental genetics, 187-188 
lineage-specific gene expression, 511-512 
molecular genetics, 399-400 
neuronal function, lix 
research with, xliv 
Caffeine, neuromodulation, 401-402 
Calcitonin gene-related peptide (CGRP) 
neuroendocrine system, 339-340 
synaptic transmission, 192 
Calcium 
hormone mediation, 129-130 
nerve cell electrical activity, 1-2 
signal transduction, visual systems, 193-194 
Calcium channels 
dystrophin-glycoprotein complex, 61-62 
molecular engineering, 426-428 
molecular studies, 529-530 
neurotransmitter storage and release mechanisms, 203 
phototransduction mechanism, retinal rods and cones, 
461-462 
prolactin secretion, 489-490 
scorpion toxin characterization, 519-520 
structure-function studies, 409 
Calmodulin, protein structure and folding, 139-140 
Calmodulin kinase II (CaMKII) gene, mammalian memory, 
424 
cAMP (cyclic AMP) 
chemical communication, sex pheromones, 257-258 
cystic fibrosis transmembrane conductance regulator 
(CFTR), 439-440 
DNA-binding proteins, gene expression, 175-176 
molecular engineering, 426-428 
olfactory system, ion channel regulation, 373-374 
second messenger system, lix 
cAMP recognition element (CRE) 
cell biological studies of memory, 219-220 
T cell receptor regulation and, 255-256 
cAMP-responsive enhancer-binding proteins (CREBs), 176 
Campylobacter jejuni, molecular biology, 487-488 
Cancer 
cell adhesion and, 195-196 
genetic modification, 247-248 
growth factors, 289-290 
lymphocyte development, molecular genetics, 231-232 
mammalian development and, 314, 315-316 
multidrug resistance, 499-500 
Carbohydrate compounds, inflammation and, 40 
Carbohydrate ligands, selectins and, 40 
Carbon assimilation, photosynthesis genetics, 503-505 
Carboxyl-terminal domain (CTD), RNA polymerase II 
structure and function, 85-86 
Carboxypeptidase Y (CPY), lysosomal hydrolase sorting, 121 
Cardiovascular disease, genetic studies, 243-244 
CCAAT displacement protein (CDP), molecular genetics of 
blood cells and, 306 
CcN motif, cell fate control, 14 
CD2 molecule, T cell recognition, 101-102 
CD4 molecule 
activation, 209-210 
cellular immune response, 181-182 
development and infection, 263-264 
human immunodeficiency virus (HIV), 178 
immune response and. Hi 
in T cells, 51-52 
CDS molecule 
cellular immune response, 181-182 
development and infection, 263-264 
immune response and. Hi 
CD 18 molecule, genetic disease and, 26 
CD28 pathway, lymphocyte development, 415-416 
CD45 antigen, protein-tyrosine phosphatases, 413-414 
cdc2 gene, cell cycle control and, 271-272 
cdk2 protein, cell cycle control and, 272 
cDNA clones 
calcium channel molecular studies, 529-530 
cerebellar gene expression and cell cycle, 180 
Down syndrome and, 237-238 
Cell adhesion 
cell structure and, xxxviii 
glycosyltransferase molecular genetics and, 267-268 
molecular basis for, 195-196 
motor neuron differentiation, 211-212 
neuron development, 335-336 
Cell adhesion molecules (CAM), 26 
Cell asymmetry, molecular genetics, 399-400 
Cell biology and regulation, research programs in, 
xxix-xxxviii 
Cell-cell interaction 
Drosophila retina, 471-472 
early embryogenesis, oncogenes, 297-298 
neural development, 207-208 
spectrin skeleton a.ssembly, 34 
transforming growth factor and, 275-276 
Cell cycle 
cell division and, xxxv-xxxvi 
colony-stimulating factor 1 receptor (CSF-IR), 371-372 
DNA replication and, 21-22 
gene expression and, 179-180, 271-272 
research trends in, xxx 
Cell death. See also Apoptosis 
Caenorhabditis elegans development, 187- 188 
visual systems, neurogenesis and, 396-398 
Cell density, differentiation and, 166-168 
Cell fate 
differentiation and, 166-168 
Drosophila retina, 471-472 
554 
