154 Proceedings of the Royal Physical Society. 
sent a more or less oval form ; others again are more pyriform 
When distended by injection, they all present convex, smooth, 
and well-defined outlines. On account of the general shape 
of the follicles, and the mode in which they are grouped to- 
gether in the lobule, they resemble in appearance a bunch of 
grapes, with which they have frequently been compared. 
The epithelial contents of the follicles are of course com- 
pletely concealed in the injected portions of the gland ; but in 
those lobules into which the injection has not passed, the 
shape and general arrangement of the secreting epithelium 
may be conveniently studied. It frequently happens that, in 
examining sections of the gland, isolated follicles may be seen, 
lying perhaps closely together, as if they had originally formed 
parts of the some lobule, but still separated by slight intervals 
from each other, having probably become detached from their 
original connections in the act of making the section. In 
these isolated follicles the secreting cells may be generally 
very distinctly seen. They form a closely packed layer, lining 
the inner surface of the membrane forming the wall of the 
follicle. Their shape is spheroidal, so that they form a true 
glandular epithelium. 
Professor Kolliker in his " Microscopic Anatomy," describes 
the pancreas as belonging to the compound racemose group of 
glands, of which the salivary glands and the mucous glands of 
the mouth may be taken as the type. In his description of 
the last-named glands, he states that the grape-like appearance 
of the ultimate follicles is owing to the fine ducts being coiled 
upon themselves, presenting at intervals numerous simple or 
compound dilatations or diverticula. He considers the glan- 
dular vesicles to be nothing more than these dilatations. In 
my examination of the injected pancreas, I have not succeeded 
in sufficiently separating from each other the various follicles 
making up a lobule, so as to state whether the view of Profes- 
sor Kolliker can be applied to the pancreas. Whether we 
hold, however, with the more generally accepted doctrine, that 
these follicles are saccular dilatations at the extremity of the 
duct, or with Professor Kolliker that they are produced by a 
coiling of the duct upon itself, the important fact still remains, 
that the membrane forming the wall of the follicles is connected 
