Drosophila embryos. These findings suggest that 
NTF-1 is a member of a family of developmentally 
regulated transcription factors that may be involved 
in directing the expression of genes such as Ubx, 
Ddc, and/fz in neuronal cells. 
Dr. Tjian is also Professor of Molecular and Cell 
Biology at the University of California at Berkeley 
and Adjunct Professor of Biochemistry and Bio- 
physics at the University of California at San 
Francisco. 
PUBLICATIONS 
Articles 
Bell, S.P, Learned, R.M., Jantzen, H.M., and Tjian, R. 1988. Functional cooperativity betw^een transcription 
factors UBFl and SLl mediates human ribosomal RNA synthesis. Science 241:1192-1197. 
Bohmann, D., Admon, A. , Turner, D.R., and Tjian, R. 1988. Transcriptional regulation by the AP-1 family of 
enhancer-binding proteins: a nuclear target for signal transduction. Cold Spring Harb Symp Quant Biol 
53:695-700. 
Courey, A.J., and Tjian, R. 1988. Analysis of Spl in vivo reveals multiple transcriptional domains, including a 
novel glutamine-rich activation motif Cell 55:887-898. 
Jackson, S.P, and Tjian, R. 1988. O-glycosylation of eukaryotic transcription factors: implications for mecha- 
nisms of transcriptional regulation. Cell 55:125-133. 
Jackson, S.P, and Tjian, R. 1989. Purification and analysis of RNA polymerase II transcription factors by using 
wheat germ agglutinin affinity chromatography. Proc Natl Acad Sci USA 86: 1781-1785. 
Kadonaga, J.T., Courey, AJ., Ladika, J., and Tjian, R. 1988. Distinct regions of Spl modulate DNA binding and 
transcriptional activation. Science 242:1566-1570. 
Mitchell, PJ., and Tjian, R. 1989. Transcriptional regulation in mammalian cells by sequence-specific DNA 
binding proteins. Science 245:371-378. 
Perkins, K.K., Dailey, G.M., and Tjian, R. 1988. In vitro analysis of the Antennapedia P2 promoter: identifica- 
tion of a new Drosophila transcription factor. Genes Dev 2:1615-1626. 
Perkins, K.K., Dailey, G.M., and Tjian, R. 1988. Novel Jun- and Fos-related proteins in Drosophila are func- 
tionally homologous to enhancer factor AP-1. EMBO J 7:4265-427^. 
Turner, R., and Tjian, R. 1989. Leucine repeats and an adjacent DNA binding domain mediate the formation 
of functional cFos/cJun heterodimers. Science 243:1689-1694. 
Williams, T, Admon, A., Liischer, B., and Tjian, R. 1988. Cloning and expression of AP-2, a cell-type-specific 
transcription factor that activates inducible enhancer elements. Genes Dev 2:1557-1569. 
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