mination (in collaboration with Susan Buchanan 
and Drs. Sinning and Michel). Crystals with recon- 
stituted Qb are being used for these experiments. A 
synchrotron x-ray source is necessary to provide 
the high primary beam intensity needed for this 
work. 
^^C. Herbicide-resistant mutants. One indication of 
the structural similarity between RCs from purple 
bacteria and from plant photosystem II is the sensi- 
tivity of both these RCs to the same herbicides. Her- 
bicide-resistant RC mutants can be obtained by cul- 
turing the bacteria in the presence of herbicide. 
X-ray diffraction experiments using the difference- 
Fourier technique are expected to indicate the 
structural changes and thereby to increase under- 
PUBLICATIONS 
standing of the mechanism of herbicide resistance 
(in collaboration with Drs. Sinning and Michel). 
II. New Projects. 
Structural studies on several other proteins in 
other biological systems have been started, to in- 
vestigate various aspects of the RC structure, such 
as membrane protein structure, electron transfer, 
and protein-protein interactions. All these studies 
are currently in the stage of crystalli2ation experi- 
ments. 
Dr. Deisenhofer is also Regental Professor and 
Professor of Biochemistry at the University of Texas 
Southwestern Medical Center at Dallas. 
Books and Chapters of Books 
Deisenhofer, J., Huber, R., and Michel, H. 1989. The structure of the photochemical reaction center from 
Rhodopseudomonas viridis and its implications for function. In Prediction of Protein Structure and the 
Principles of Protein Conformation (Fasman, G.D., Ed.). New York: Plenum, pp 99-116. 
Deisenhofer, J., and Michel, H. 1988. The crystal structure of the photosynthetic reaction center from 
Rhodopseudomonas viridis. In The Photosynthetic Bacterial Reaction Center: Structure and Dynamics 
(Breton, J., and Vermeglio, A., Eds.). New York: Plenum, pp 1-3. 
Deisenhofer, J., and Michel, H. 1988. The crystal structure of the photosynthetic reaction center from 
Rhodopseudomonas viridis. In Transport Through Membranes: Carriers, Channels, and Pumps. Proceed- 
ings of the 21st Jerusalem Symposium on Quantum Chemistry and Biochemistry, 1988 (Pullman, A., Jort- 
ner, J., and Pullman, B., Eds.). Dordrecht: Kluwer Academic, pp 507-512. 
Deisenhofer, J. , and Michel, H. 1989. The crystal structure of the photosynthetic reaction center from 
Rhodopseudomonas viridis. In Photochemical Energy Conversion: Proceedings of the Seventh Interna- 
tional Conference on Photochemical Conversion and Storage of Solar Energy, Evanston, Illinois, USA, 
1988 (Norris, J.R., Jr., and Meisel, M., Eds.). New York: Elsevier Science, pp 232-237. 
Deisenhofer, J., and Michel, H. 1989. The 3-D structure of the photosynthetic reaction center from 
Rhodopseudomonas viridis. In Molecular Electronic Devices. Proceedings of the 3rd International Sym- 
posium on Molecular Electronic Devices, Arlington, Virginia, 6-8 October 1986 (Carter, F.L., Siatkowski, 
R.E., and Wohltjen, H., Eds.). Amsterdam: Elsevier Science, pp 621-631. 
Treutlein, H., Niedermeier, C, Schulten, K., Deisenhofer, J. , Michel, H., Briinger, A. , and Karplus, M. 1988. 
Molecular dynamics simulation of the primary processes in the photosynthetic reaction center from 
Rhodopseudomonas viridis. In Transport Through Membranes: Carriers, Channels, and Pumps. Proceed- 
ings of the 21st Jerusalem Symposium on Quantum Chemistry and Biochemistry, 1988 (Pullman, A., Jort- 
ner, J., and Pullman, B., Eds.). Dordrecht: Kluwer Academic, pp 513-525. 
Treutlein, H., Schulten, K., Deisenhofer, J., Michel, H., Brunger, A., and Karplus, M. 1988. Molecular dynam- 
ics simulation of the primary processes in the photosynthetic reaction center from Rhodopseudomonas 
viridis. In The Photosynthetic Bacterial Reaction Center: Structure and Dynamics (Breton, J., and Ver- 
meglio, A., Eds.). New York: Plenum, pp 139-150. 
Treutlein, H., Schulten, K., Niedermeier, C, Deisenhofer, J. , Michel, H., and Devault, D. 1988. Electrostatic 
control of electron transfer in the photosynthetic reaction center of Rhodopseudomonas viridis. In The 
Photosynthetic Bacterial Reaction Center: Structure and Dynamics (Breton, J., and Vermeglio, A., Eds.). 
New York: Plenum, pp 369-377. 
Continued 
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