94 CARDIAC 
Tabmi I. — Composition of Diets Consumed per Day in 
Grams 
"Stock" 
"MUd" 
"Severe" 
"Moderate" 
Ingredients 
(PS) 
(PSC) 
(TSC) 
(SO 
Casein 
143 
143 
95 
152 
Sucrose 
227 
227 
140 
224 
Butter 
67 
57 
87 
139 
Peanut Oil 
57 
57 
87 
139 
Salt Mix, Wesson 
30 
30 
30 
48 
Vitamin Mix 
12.5 
12.5 
12.6 
20 
Choline Chloride 
2.5 
2.5 
2.6 
4 
Cellulose 
121 
113 
24.5 
41 
Cholesterol 
0 
8 
14 
22 
Sodium Cholate 
0 
0 
7 
11 
Propylthiouracil 
0 
0 
0.5 
0 
Total 
660 
650 
600 
800 
Calories 
2,506 
2,506 
2,506 
4,006 
diets and a stock diet used and also the amounts 
of each ingredient consumed per day. When the 
severe (TSC) diet was used, it v^^as mixed with 
MODELS 
commercial mash for the first three weeks of a 
conditioning period in the following propor- 
tions : first week Va TSC, %■ mash ; second week 
1/2 TSC, 1/2 mash; third week TSC, Va mash; 
fourth week and thereafter, full TSC diet. Dur- 
ing the course of the experiment when any 
swine appeared weak and less active than usual, 
a portion of the TSC diet was replaced with 
mash for few days until the swine recovered 
and regained his strength. 
X-irradiation of 1,500 r was given to the pre- 
cordial region of pentobarbital sodium anesthe- 
tized swine twice at 4-7 week intervals (Tables 
II-V) by using a ^"Co-teletherapy unit at a dis- 
tance of 60 cm with an 8.7 cm square portal. In 
early experiments, several months on the diet 
elapsed before x-irradiation was given. In later 
experiments (Series II), we have found 8 weeks 
Table II. — Data Concerning Swine Fed Severe Altherogenic Diet and X-irradiated Twice, Surviving Until 
Termination of Experiment 
Serum 
Coronary Arteries 
Pi« 
No. 
On diet 
before 
1st x-ray 
wks. 
Interval 
between 
x-rays 
wks. 
Survived 
after 1st 
x-ray 
wks. 
Weight, kg 
Cholesterol 
mg% 
Avg. lum- 
inal diam. 
mm 
Avg. wall 
thickness 
mm 
Virtual 
or total 
occlusion 
Infarct 
TSC 
Init. 
Final 
Init. 
Final 
Rec* 
Old 
1 
4 
4 
12 
15.5 
247 
.80 
.23 
2 
8 
7 
28 
23.4 
33.9 
55 
209 
.58 
.48 
+ 
+ 
3 
29 
6 
11.6 
15.5 
26.4 
169 
1176 
.40 
.73 
4- 
+ 
+ 
4 
39 
4 
9 
9.1 
24.5 
114 
532 
.63 
.46 
+ 
+ 
+ 
5 
40.6 
6 
16.5 
15.9 
26.7 
59 
1300 
.73 
.43 
6 
40.6 
6 
16.5 
16.5 
120 
739 
.68 
.63 
+ 
+ 
+ 
7 
40.6 
6 
16.5 
150 
543 
.73 
.30 
+ 
8 
40.5 
6 
15.6 
21.3 
38.4 
89 
1119 
.33 
.68 
+ 
+ 
9 
40.6 
6 
14 
15.7 
57 
98 
668 
.70 
.50 
+ 
+ 
+ 
10 
40.6 
6 
17 
18 
65 
109 
678 
.58 
.35 
+ 
+ 
• Recent infaret. 
Table III. — Data Concerning Swine Fed Severe Atherogenic Diet and X-irradiated Twice, Dying Suddenly Prior 
to Termination of Experiment 
Coronary Arteries 
Pig 
No. 
On diet 
before 
1st x-ray 
wks. 
Interval 
between 
x-rays 
wks. 
Survived 
after 1st 
x-ray 
wks. 
Weight, kg 
Serum 
Cholesterol, mg% 
Avg. Lum- 
inal diam. 
mm 
Avg. wall 
thickness 
mm 
virtual or 
total 
occlusion 
Infarct 
TSC 
Init. 
Final 
Init. 
Final 
Rec* 
Old 
11 
10 
6 
11 
16.8 
15.9 
98 
1136 
+ 
+ 
+ 
12 
4 
7 
17 
18.2 
23.6 
81 
1620 
.43 
.65 
+ 
IS 
8 
7 
16 
20 
36.8 
95 
3020 
.50 
.76 
+ 
+ 
+ 
14 
le 
6 
10 
23.6 
30 
88 
1740 
.63 
.38 
+ 
+ 
IS 
10 
6 
12 
16.1 
31.4 
68 
1400 
.40 
.68 
+ 
+ 
+ 
16 
8 
7 
14 
15.2 
30 
95 
1840 
.26 
.90 
+ 
+ 
+ 
17 
29 
6 
8 
13.2 
22.5 
IOC 
1265 
.23 
.66 
+ 
+ 
+ 
IS 
29 
6 
9.6 
12.3 
18.8 
122 
1382 
.65 
.60 
+ 
+ 
+ 
19 
30 
6 
10 
10.2 
34.1 
81 
1195 
.53 
.60 
+ 
+ 
+ 
20 
46.5 
4 
4.6 
29.3 
37 
94 
1380 
.93 
.30 
21 
40.5 
4 
13 
29.5 
52.6 
65 
618 
.65 
.66 
+ 
4- 
22 
40.6 
6 
16 
24.6 
40.5 
95 
654 
.93 
.28 
+ 
23 
39 
6 
16 
8 
13.6 
105 
951 
.73 
.23 
4- 
24 
40.6 
6 
16 
16 
72 
183 
584 
.58 
.66 
+ 
4- 
26 
40.6 
6 
18 
25 
63.5 
90 
586 
.98 
.36 
+ 
26 
40.5 
6 
18 
26 
72.8 
103 
1149 
80 
.30 
+ 
+ 
27 
40.6 
6 
18.6 
22 
36.6 
99 
1597 
.70 
.63 
+ 
4- 
4- 
28 40.5 
• Recent infarct. 
6 
18.6 
14.5 
21.6 
95 
977 
.53 
.48 
+ 
+ 
