266 
PULMONARY MODELS 
studies on this, and the gradient is much re- 
duced with methylprednisolone. It's also much 
reduced in the animal with the reimplanted 
lung. 
R. E. Clark, Washington University, St. 
Louis, Missouri : A superb presentation as al- 
ways. Dr. Webb. I'd like to ask you whether 
you've found any difference after shock with 
the use of hyperosmolar agents, particularly 
with regard to the thickness of the alveolar 
wall? 
Dr. Webb : We have not used the very hyper- 
osmotic solutions so I really can't answer your 
question. We used only the low molecular 
weight dextran which does not add to much, 
as you know. 
We have tried to use lasix and things of this 
nature to see if this would help get rid of some 
pulmonary edema. It has been of little value. 
Dr. Clark : Have you used heparin at all in 
any of these preparations ? 
Dr. Webb : All of these dogs were heparinized 
(3 mg. per kilogram), and as you can see, it 
does not prevent the red cell agglutination, etc. 
