M. P. KAYE AND J. B. PACE 
361 
OXYGENRTOR TEST RESULTS 
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FiGUHE 5. — Comparison of platelet counts of animals subjected to bypass with "T" (bubble) oxygenator and "D" 
membrane oxygenator. 
SUMMARY 
The use of the calf as an experimental animal 
has become commonplace in studies dealing 
with the artificial heart, its components and 
other heart and lung assist devices. Much perti- 
nent information concerning surgical and 
anesthetic techniques in calves has been commu- 
nicated to investigators as a result of this Con- 
ference. One of the most common problems 
dealt v^ith was that of respiratory care of the 
calf subjected to anesthesia. Halothane is the 
apparent anesthetic of choice. The use of barbi- 
turates was in most instances accompanied by a 
high mortality even when the very short-acting 
drugs were used. Large tidal volumes 
(1400-1600 ml) and high pressures (30-40 cm 
HoO) were found to be necessary if a satisfac- 
tory post-operative course was desired. 
During cardiac manipulation, it has been 
noted that the calf is prone to a high incidence 
of dysrhythmias. The use of lidocaine prior to 
manipulation has been successful in preventing 
these rhythm disturbances. In calves subjected 
to coronary occlusion for the production of car- 
diogenic shock, severe disturbances of rhythm 
(frequently ventricular fibrillation) are re- 
ported. The incidence of these arrhythmias has 
been decreased or abolished by infusion of insu- 
lin, dextrose arid potassium. 
The use of dogs as experimental animals in 
