SURGERY AND TRANSPLANTATION 
435 
this time. We found that in contrast to the find- 
ings of Donald and Shepherd a healthy dose of 
propanolol in a denervated dog very, very seri- 
ously impairs his response to running, whether 
one is considering mild or severe exertion. We 
also found almost complete aggregation of most 
of the rate dependent parameters during run- 
ning. 
