458 
HEMATOLOGY 
Although in routine veterinary work canine 
blood is frequently not tested for compatibility 
before transfusion, in a research laboratory set- 
ting where sensitization by prior transfusions 
may be common, typing should be done to avoid 
the morbidity which may result from transfu- 
sion of incompatible blood and to avoid the mor- 
tality seen in hemolytic disease of newborn 
pups. 
SUMMARY 
The major erythrocyte antigenic systems of 
sheep, cattle and dogs are discussed. 
The discoveries of the ovine R-0 and X-Z sys- 
tems are reviewed. Major emphasis is placed on 
a description of the ML system and its relation- 
ship to the intracellular potassium concentra- 
tion of the sheep erythrocyte. 
Eleven major cattle blood groups are briefly 
reviewed. The complexity of the B system is 
noted, and there is a discussion of the J 
antigen and its relationship to cells and serum. 
The discussion of canine blood groups in- 
cludes a review of the discovery of the A system 
and a description of transfusion reactions in- 
volving Ai incompatibility. 
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