708 
PHARMACOLOGY 
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DISCUSSION 
Chairman Cohen : I'd like to ask Dr. Cochin 
if there are any specific EEG effects that one 
can monitor in an animal, such as a monkey or 
a dog, to indicate whether or not there is any 
hallucinogenic action going on after the admin- 
istration of, say, mescaline? 
Dr. Cochin : In some work which is provoca- 
tive but not conclusive. There are EEG changes 
with other central-reacting drugs that one can 
monitor even in the rat ; with morphine, for in- 
stance, and the antagonists. With mescaline, 
EEG changes in the dog are really suggestive, 
but I think this is a field that should be explored 
because, for those of us who have worked with 
the drug, there is no question that something 
has happened to those animals that can only be 
described as an hallucinatory experience. They 
look and jump at imaginary objects. They ex- 
hibit all sorts of bizarre behavior. 
