796 
ANATOMY AND PATHOLOGY 
Figure 32. — Site of attachment of electromagnetic blood 
flow transducer (1 mm lumen diameter) for measure- 
ment of basilar blood flow. 
24. Anderson, W. D., and Kubicek, W. Effects of 
betahistine HCl, nicotinic acid, and histamine on ' 
basilar blood flow in anesthetized dogs. Stroke 2: 
409-415, 1971. 
25. Anderson, W. D., and Weber, A. F. Normal i 
arterial supply to the ruminant (ovine) stomach. 
J. Anim. Sci. 28:379-382, 1969. 
26. Anderson, W. D. Surgical anatomy associated with 
rumenoreticulectomy in the sheep. Am. J. Vet. Res. 
30:1631-1636, 1969. 
27. Kaplan, H. A. and Ford, D. U.The Brain Vascu- 
lar System, New York, N.Y., Elsevier. 
28. Kubicek, W., and Anderson, W. D. Effects of 
betahistine HCl (Sere) on recovery from induced 
hypovolemic shock in dogs, VI European Confer- 
ence on Microcirculation, Proceedings, Aalborg, 
Denmark, S. Karger, Basel (Switzerland), 160- 
163, 1971. 
DISCUSSION 
Chairman Kusserow: Thank you, Dr. An- 
derson. As you stressed, for those concerned 
with the research area of prosthetic vascular 
implants, the differences in anatomical struc- 
ture of the vascular system in the various spe- 
cies is a very important matter. Are there 
questions? 
Jeffrey L. Peters, University of Utah, Salt 
Lake City: Let's say one blocks off the left 
Effects of Betahistine Hydrochloride (Sere), 
Histamine and Nicotinic Acid (Niacin) 
on Normalized Bosilor Blood Flow and Femoral Arteriol Pressure 
18. Mazzoni, a. Internal auditory canal arterial re- 
lations at the porus acusticus. Ann. Oto. Rhinol. 
Laryng. 78:1-18, 1969. 
19. Mazzoni, A., and Hansen, C. C. Surgical anatomy 
of the arteries of the internal auditory canal. Arch. 
Otolaryng. 91:128-135, 1969. 
20. Alford, B. R., Shaver, E. F., Rosenberg, J. J., and 
Guilford, F. R. Physiologic and histopathologic 
effects of microembolism of the internal auditory 
artery. Trans. Am. Otal. Soc. 58:110-130, 1965. 
21. Bernstein, J. M., and Silverstein, M. Anterior 
cerebellar and labyrinthine arteries. A study in the 
cat. Arch. Otolaryng. 83:402-435, 1966. 
22. Perlman, H. B., Kimura, R., and Fernandes, C. 
Experiments on temporary obstruction of the in- 
ternal auditory artery. Laryngoscope 69:591-600, 
1959. 
23. HiLGER, J. A. Vasomotor labyrinthine ischemia, 
Ann. Oto. Rhinol. Laryng. 59:1102-1108, 1950. 
200 
Betahistine Histamine Nicotinic 
Hydrochloride Phosphate Acid 
O.ll mg/kg 0.025mg/kg 1,1 mg/kg 
Figure 33. — Mean changes (± SEM) in basilar blood 
flow in six experiments in anesthetized dog following 
intravenous injection of betahistine hydrochloride 
(Sere), histamine phosphate and nictotinic acid 
(Niacin). 
